[Neuroimaging of idiopathic normal pressure hydrocephalus--current concepts].
[Neuroimaging of idiopathic normal pressure hydrocephalus--current concepts].
复制标题
[特发性正常压脑积水的神经影像学——当前概念]。
DOI：
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发表时间：
2008
期刊：
影响因子：
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通讯作者：
F. Yamashita
中科院分区：
文献类型：
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作者：
M. Sasaki;F. Yamashita
神经影像学在特发性正常压力脑积水（iNPH）的诊断和治疗中发挥着重要作用。除了埃文斯指数为 0.3 或更高的心室扩张外，高凸/中线区域蛛网膜下腔的紧张以及外侧裂和基底池的同时扩张也是 iNPH 的特征。基于体素的形态测量技术可以很容易地确定这些发现的有效性。脑室周围高信号、导水管中明显的血流空洞、心室反流和造影剂淤滞被认为在鉴别诊断和患者管理中的优势有限。脑血流量测量可能有助于区分 iNPH 和其他疾病；然而，由于蛛网膜下腔不成比例的缩小和扩张而导致的部分体积效应可能会在后处理和解释过程中导致重大错误。
Neuroimaging plays an important role in the diagnosis and management of the idiopathic normal pressure hydrocephalus (iNPH). In addition to a ventricular dilatation with an Evans index of 0.3 or more, a tightness of the subarachnoid space in the high convexity/midline areas with a concurrent dilatation of the sylvian fissure and basal cistern is characteristic in iNPH. Voxel-based morphometry techniques can readily determine the validity of these findings. Periventricular hyperintensity, marked flow void in the aqueduct, and ventricular reflux and stasis of contrast agents are believed to have limited advantages in differential diagnosis and patient management. Cerebral blood flow measurement may help in discriminating iNPH from other disorders; however, partial volume effects due to disproportionate narrowing and dilatation of the subarachnoid space can cause substantial errors during post-processing and interpretation.