Nitrate and nitrite concentrations in rabbit saliva - Comparison with rat saliva
Nitrate and nitrite concentrations in rabbit saliva - Comparison with rat saliva
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DOI：
10.1016/j.etap.2006.07.007
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发表时间：
2007-01-01
影响因子：
4.3
通讯作者：
Thorin, C.
中科院分区：
文献类型：
--
作者：
Djekoun-Bensoltane, S.;Kammerer, M.;Thorin, C.
本研究旨在探讨家兔对硝酸盐药理毒理学研究的兴趣。21名女性被给予1,300和600毫克/升的硝酸盐饮用水11周。分析唾液和血液中的硝酸盐/亚硝酸盐。与在大鼠中观察到的相反，摄入的硝酸盐量和唾液中的硝酸盐量之间存在线性关系。然而，唾液中的亚硝酸盐浓度仍然很低，兔子口腔中的硝酸还原酶活性似乎很弱。(c)2006 Elsevier B. V.保留所有权利。
The purpose of this work was to investigate the interest of rabbits for studying pharmacology and toxicology of dietary nitrate. Twenty-one females were given 1,300 and 600 mg/l nitrate in drinking water for 11 weeks. Saliva and blood were analysed for nitrate/nitrite. There is a linear relationship between the amounts of nitrate ingested and amount of nitrate in saliva, contrary to what is observed in rats. However, salivary nitrite concentrations remain low, and nitrate reductase activity in the oral cavity of the rabbit seems very weak. (c) 2006 Elsevier B.V. All rights reserved.