Generalized background qEEG abnormalities in localized symptomatic epilepsy
Generalized background qEEG abnormalities in localized symptomatic epilepsy
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DOI：
10.1016/s0013-4694(98)00026-1
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发表时间：
1998-06-01
期刊：
影响因子：
--
通讯作者：
Valdés, P
中科院分区：
文献类型：
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作者：
Díaz, GF;Virués, T;Valdés, P
研究了起源于额叶或颞叶的局限性症状性癫痫（LSE）患者的EEG背景活动的频谱特征。获得所有10/20系统导联的高分辨率频谱的Z值和EEG参数（xi alpha）模型的测量值，并与对照组中获得的Z值进行比较。在LSE的综合征变体之间以及在数字EEG（dEEG）中有或没有阵发性活动的患者亚组之间进行比较。在患者中发现α范围的能量显著减少和θ范围的轻度增加，与癫痫的综合征变体无关。这些偏离正常值的现象在头皮上广泛存在，与抗癫痫药物无关。非参数检验显示定量EEG异常的幅度与dEEG中阵发性活动的量之间呈正相关。减慢的平均频率的α分量的光谱，在α范围内的功率的实际减少和增加的θ范围内解释的结果。本文最引人注目的发现是局灶性癫痫可能对EEG的频率组成产生广泛的影响。(C)1998爱思唯尔科学爱尔兰有限公司保留所有权利。
Spectral features of EEG background activity were studied in patients with localized symptomatic epilepsy (LSE), with origin in the frontal or temporal lobes. Z-values of high resolution spectra and measures of the parametric (xi alpha) model of the EEG were obtained for all 10/20 System leads and were compared with those obtained in a control group. Comparisons were performed between syndromic Variants of LSE and between subgroups of patients with or without paroxysmal activity in their digital EEGs (dEEG). Marked reduction of the energy in the alpha range and a mild increase in the theta range were found in the patients, unrelated to the syndromic variant of the epilepsy. These deviations from normality were widespread on the scalp and were not related to antiepileptic medication. Non-parametric testing showed a positive correlation between the magnitude of the quantitative EEG abnormalities and the amount of paroxysmal activity in the dEEG. Slowing of the mean frequency of alpha components of the spectra, an actual decrease of power in the alpha range and an increase in the theta range explained the results. The most striking finding of this paper is that focal epileptogenesis may have a generalized impact in the frequency composition of EEG. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.