Prophylactic antibiotics in orthopaedic surgery

Prophylactic antibiotics in orthopaedic surgery
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DOI:
10.5435/00124635-200805000-00007
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发表时间:
2008-05-01
影响因子:
3.2
通讯作者:
Prokuski, Laura
Prokuski, Laura
中科院分区:
医学2区
文献类型:
--
作者:
Prokuski, Laura

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在骨科手术中使用预防性抗生素可有效减少髋关节置换术、脊柱手术和骨折切开复位内固定手术部位感染。为了最大限度地发挥预防性抗生素的有益作用,同时最大限度地减少不良反应,必须选择正确的抗菌药物,必须在切口前给药,给药时间不应超过24小时。
The use of prophylactic antibiotics in orthopaedic surgery is effective in reducing surgical site infections in hip and knee arthroplasty, spine surgery, and open reduction and internal fixation of fractures. To maximize the beneficial effect of prophylactic antibiotics while minimizing adverse effects, the correct antimicrobial agent must be selected, the drug must be administered just before incision, and the duration of administration should not exceed 24 hours.