The effect of cingulate lesions on social behaviour and emotion
The effect of cingulate lesions on social behaviour and emotion
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DOI：
10.1016/s0028-3932(02)00325-1
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发表时间：
2003-01-01
期刊：
影响因子：
2.6
通讯作者：
Passingham, RE
中科院分区：
文献类型：
--
作者：
Hadland, KA;Rushworth, MFS;Passingham, RE
人类扣带皮层的功能和结构神经成像已经确定该区域与情绪和社会认知有关，并表明扣带病理可能与情绪和社会行为障碍有关。然而，从损伤研究中还不清楚扣带皮层对情感和社会行为的重要性。研究人员对三只猕猴的双侧扣带皮层进行了损伤，并将它们的社会互动与对照组进行了比较。随后，在三个对照组中制作扣带病变，并在手术前后比较它们的行为。扣带病变与社交互动减少、与他人相处的时间减少、发声减少有关，但与操纵无生命物体的次数增加有关。研究结果与扣带在社会行为和情感中的作用是一致的。2003爱思唯尔科学有限公司版权所有。
Functional and structural neuroimaging of the human cingulate cortex has identified this region with emotion and social cognition and suggested that cingulate pathology may be associated with emotional and social behavioural disturbances. The importance of the cingulate cortex for emotion and social behaviour, however, has not been clear from lesion studies. Bilateral lesions in the cingulate cortex were made in three macaques and their social interactions were compared with those of controls. Subsequently, cingulate lesions were made in the three controls and their behaviour was compared before and after surgery. Cingulate lesions were associated with decreases in social interactions, time spent in proximity with other individuals, and vocalisations but an increase in manipulation of an inanimate object. The results are consistent with a cingulate role in social behaviour and emotion. (C) 2003 Elsevier Science Ltd. All rights reserved.