The distribution of epithelial membrane antigen in the kidney and its tumours
The distribution of epithelial membrane antigen in the kidney and its tumours
复制标题
上皮膜抗原在肾脏及其肿瘤中的分布
作者：
S. Fleming;G. Lindop;A. Gibson
使用多克隆抗 EMA 抗血清和免疫过氧化物酶-抗过氧化物酶技术 (PAP) 研究了上皮膜抗原 (EMA) 在肾脏及其肿瘤中的分布。检查的 12 个胎儿肾脏和 10 个成人肾脏显示 EMA 仅限于远端肾小管或其胚胎前体。对55个原发性肾肿瘤的检查显示，EMA存在于上皮肿瘤、肾母细胞瘤的管状上皮上，但不存在于间质肿瘤细胞或肾母细胞瘤的未分化区域上。
The distribution of epithelial membrane antigen (EMA) in the kidney and its tumours has been studied using a polyclonal anti‐EMA antiserum and the immunoperoxidase‐antiperoxidase technique (PAP). Twelve fetal and 10 adult kidneys examined showed EMA to be confined to the distal tubular or their embryological precursors. The examination of 55 primary renal tumours showed EMA to be present on the epithelial tumours, on tubular epithelium in nephroblastoma, but not on mesenchymal tumour cells nor on undifferentiated areas of nephroblastoma.