Motion of objects embedded in lipid bilayer membranes: Advection and effective viscosity
Motion of objects embedded in lipid bilayer membranes: Advection and effective viscosity
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DOI：
10.1063/1.5121418
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发表时间：
2019-09-28
影响因子：
4.4
通讯作者：
Brown, Frank L. H.
中科院分区：
文献类型：
--
作者：
Camley, Brian A.;Brown, Frank L. H.
提出了一种界面正则化的Stokeslet格式来预测固体的运动（例如，蛋白质或凝胶相结构域）包埋在流动的脂质双层膜内。该方法提供了一个数值的路线来计算速度和角速度在复杂的流场，是不适合简单的Faxen近似。此外，当施加到剪切运动，计算产生的有效表面粘度的稀刚体负载膜的预测。在圆柱形蛋白质的情况下，有效的粘度计算相比，从文献中的两个先前的分析预测。有效的粘度预测的棒状物体在膜中的稀悬浮液。
An interfacial regularized Stokeslet scheme is presented to predict the motion of solid bodies (e.g., proteins or gel-phase domains) embedded within flowing lipid bilayer membranes. The approach provides a numerical route to calculate velocities and angular velocities in complex flow fields that are not amenable to simple Faxen-like approximations. Additionally, when applied to shearing motions, the calculations yield predictions for the effective surface viscosity of dilute rigid-body-laden membranes. In the case of cylindrical proteins, effective viscosity calculations are compared to two prior analytical predictions from the literature. Effective viscosity predictions for a dilute suspension of rod-shaped objects in the membrane are also presented.