Liver transplantation in biliary atresia with concomitant hepatoma.
Liver transplantation in biliary atresia with concomitant hepatoma.
复制标题
肝移植治疗胆道闭锁合并肝癌。
DOI：
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发表时间：
1972
期刊：
影响因子：
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通讯作者：
T. Starzl
中科院分区：
文献类型：
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作者：
J. V. Wyk;CG Halgrimson;G. Giles;J. Lilly;G. Martineau;T. Starzl
先天性胆道闭锁在肝移植的候选名单中排名靠前，并且在我们机构的一系列报告中构成了肝脏替代的单一最常见适应症。25在以这种方式治疗的2例患者中，肝细胞瘤存在于移植时切除的异位肝脏中。在1例病例中，术前已诊断为肝癌，但在另1例病例中，标本中发现肿瘤令人惊讶。
原发性肝细胞癌发生在先天性胆道闭锁引起的肝硬化患者是不常见的。Absolon在一份关于胆管闭锁的胸导管淋巴引流的报告中首次提到了这种关联。1 Okuyama随后报告了3例病例。20 Fish10和Deoras。7。
本文报告了上述2例先天性胆道闭锁伴肝癌行肝脏替代治疗的病例。
Congenital biliary atresia ranks high in the candidacy list for hepatic transplantation, and constitutes the single most frequent indication for liver replacement in a series reported from our institution.25 In 2 patients treated in this manner, hepatoma was present in the cirrhotic livers, excised at the time of transplantation. The diagnosis of hepatoma had been made pre-operatively in 1 instance, but in the other the finding of a tumour in the specimen was a surprise.
The occurrence of primary liver cell carcinoma in livers with pre-existing cirrhosis due to congenital biliary atresia is unusual. Absolon first mentioned this association in a report on thoracic duct lymph drainage for bile duct atresia.1 Three cases were subsequently reported by Okuyama.20 Fish10 and Deoras.7.
This communication reports on the 2 above-mentioned cases of congenital biliary atresia with concomitant hepatoma treated by hepatic replacement.