Perspectives on holoprosencephaly: Part II. Central nervous system, craniofacial anatomy, syndrome commentary, diagnostic approach, and experimental studies.
Perspectives on holoprosencephaly: Part II. Central nervous system, craniofacial anatomy, syndrome commentary, diagnostic approach, and experimental studies.
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对前脑无裂畸形的看法：第二部分。
DOI：
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发表时间：
1992
期刊：
影响因子：
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通讯作者：
K. Sulik
中科院分区：
文献类型：
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作者：
Cohen Mm;K. Sulik
本文对前脑无裂疾病进行了最新的分析综述。深入讨论中枢神经系统的发现和颅面解剖学。相关的异常和综合症通过综合症评论进行更新，试图将持久的综合症与相关的异常和虚假实体分开。还讨论了可能模拟前脑无裂疾病的各种病症的鉴别诊断。回顾了前脑无裂畸形的各种实验方法，表明前脑无裂畸形在病因学和发病机制上似乎具有异质性。
This paper presents an updated analytic review of the holoprosencephalic disorders. Central nervous system findings and craniofacial anatomy are discussed in depth. Associated anomalies and syndromes are updated with a syndrome commentary that attempts to separate durable syndromes from associated anomalies and spurious entities. The differential diagnosis of various conditions that may simulate the holoprosencephalic disorders is also discussed. Various experimental approaches to holoprosencephaly are reviewed, indicating that holoprosencephaly appears to be both etiologically and pathogenetically heterogeneous.