Determinants of Cardiac Ejection Fraction for the Patients with DobutamineStress Echocardiography
Determinants of Cardiac Ejection Fraction for the Patients with DobutamineStress Echocardiography
复制标题
多巴酚丁胺负荷超声心动图患者心脏射血分数的决定因素
DOI:
10.4172/2161-1165.1000307
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发表时间:
2017
期刊:
影响因子:
5.4
通讯作者:
R. Das
中科院分区:
文献类型:
--
作者:
R. Das
Objectives: The current article aims to identify the determinants of the baseline cardiac ejection fraction, and
also the ejection fraction on dobutamine dose of 558 heart patients who underwent dobutamine stress
echocardiography (DSE).
Background: Little is known about the determinants of ejection fraction with DSE.
Methods: The response ejection fraction is positive, heterogeneous, and gamma distributed, so joint generalized
linear gamma model fitting is used.
Results: The baseline cardiac ejection fraction (baseEF) increases as the peak heart rate (pkhr) (P=0.0247), or
systolic blood pressure (sbp) (P=0.0007), or ejection faction on dobutamine (dobEF) (P<0.001) increases. The
baseEF decreases as the double product (DP) of peak heart rate and systolic blood pressure (dp) (P=0.0017), or
dobutamine dose given (dose) (P=0.0255) increases. The baseEF increases of the cardiac patients with DSE who
have recent angioplasty (newPTCA) (P=0.0101), or history of myocardial infraction (hxofMI) (P=0.0658), or baseline
electrocardiogram diagnosis (ecg) at normal level (P=0.0555). The baseEF increases of the cardiac patients with
DSE who have not resting wall motion abnormality on echocardiogram (ECDG) (restwma) (P=0.0003), or positive
stress echocardiogram (posSE) (P<0.001), or history of angioplasty (hxofPTCA) (P=0.0384). On the other hand, the
ejection fraction on dobutamine dose (dobEF) increases as the dp (P=0.0007), or dose (P=0.0110), or baseEF
(P<0.001) increases. Also the dobEF decreases as the sbp (P=0.0012) increases. The dobEF increases of the
cardiac patients with DSE who have posSE (P<0.001), or new myocardial infraction (newMI) (P=0.0054), or recent
bypass surgery (newCABG) (P=0.0049). Again, the dobEF increases of the cardiac patients with DSE who have not
newPTCA (P=0.0708). Also the dobEF decreases of the cardiac patients with DSE who have heavy history of
smoking (hxofCig) (P=0.0261).
Conclusion: Impacts of pkhr, basal blood pressure, sbp, mbp, dobutamine dose, heart conditions, heavy
smoking and others on baseEF and dobEF have been identified based on probabilistic modelling. Most of the
present findings and their effects are almost new in the cardiac ejection fraction diagnosis literature.
影响因子:
39.3
作者:
de Simone, Giovanni;Gottdiener, John S.;Maurer, Mathew S.
通讯作者:
Maurer, Mathew S.
影响因子:
24
作者:
Dávila-Román,VG;Waggoner,AD;Sicard,GA;Geltman,EM;Schechtman,KB;Pérez,JE
通讯作者:
Pérez,JE
影响因子:
158.5
作者:
Owan, Theophilus E.;Hodge, David O.;Redfield, Margaret M.
通讯作者:
Redfield, Margaret M.