Glomerulonephritis and malignancy: A population-based analysis
Glomerulonephritis and malignancy: A population-based analysis
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DOI：
10.1046/j.1523-1755.2003.00771.x
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发表时间：
2003-02-01
影响因子：
19.6
通讯作者：
Storm, HH
中科院分区：
文献类型：
--
作者：
Birkeland, SA;Storm, HH
背景。肾小球肾炎和恶性肿瘤之间的关联先前在临床系列中被发现和丢弃，但据我们所知从未在基于人群的环境中进行过测试。丹麦肾活检登记包括1985年以来进行的所有肾活检。通过一个独特的个人识别号码，登记处的每个人都与国家人口登记处和丹麦癌症登记处联系起来。将形态学、肾小球疾病患者活检后的癌症发生率与普通丹麦人群进行比较，考虑性别、年龄、日历期和活检后的时间，并计算观察到至预期率的95%置信区间（95% CI），假设泊松分布。癌症发生分层至
Background. An association between glomerulonephritis and malignant tumors has previously both been found and discarded in clinical series, but to our knowledge never has been tested in a population-based setting.Methods. The Danish Kidney Biopsy Registry includes all kidney biopsies performed from 1985. Using a unique personal identification number, each person in the registry to the National Population Registry and the Danish Cancer Registry were linked. Cancer occurrence after the biopsy was compared in patients with morphological, glomerular diseases with that of the general Danish population, taking into account sex, age, calendar period and time since biopsy, and the 95% confidence interval (95% CI) for the observed-to-expected rates was calculated, assuming a Poisson distribution. Cancer occurrence was stratified to