High-resolution manometry of pharyngeal swallow pressure events associated with head turn and chin tuck.
High-resolution manometry of pharyngeal swallow pressure events associated with head turn and chin tuck.
复制标题
DOI：
10.1177/000348941011900602
复制
发表时间：
2010-06
期刊：
影响因子：
--
通讯作者：
Ciucci MR
中科院分区：
文献类型：
--
作者：
McCulloch TM;Hoffman MR;Ciucci MR
使用高分辨率测压（HRM）量化吞咽动作对咽部压力事件的影响。七名受试者在三种不同的姿势条件下吞下了多个5 ml的水丸：中立，头部转动和下巴收紧。使用36传感器HRM导管记录压力和时间事件。我们分析了腭咽和舌根区域的最大压力、压力增加率、压力梯度和压力高于基线的持续时间。在上食管括约肌（UES）区域，我们分析了压力下降的持续时间、打开期间的最小压力以及UES打开前后的最大压力。操作对最大压力、压力增加率或咽喉或舌根区域的压力梯度没有显著影响。头转向时，咽部压力高于基线的持续时间明显较长。中性吞咽的吞咽前最大UES压力显著大于头部转动，缩颏吞咽后最大压力显著较低。两种操作似乎都延长了UES压力下降的持续时间，但都没有达到显著性。HRM允许最佳的空间和时间分辨率在记录压力事件沿着长度的咽部和揭示以前未检测到的任务依赖性压力和时间差异在下巴收紧和头部转动在健康成人。这些动作似乎对UES的影响程度大于对咽喉和舌根的影响。进一步研究旨在量化其他操作和推注对正常和紊乱受试者咽部压力事件产生的影响，可能会导致假设驱动的最佳个性化吞咽治疗。
To quantify the effect of swallowing maneuvers on pharyngeal pressure events using high resolution manometry (HRM). Seven subjects swallowed multiple, five ml water boluses in three different postural conditions: neutral, head turn, and chin tuck. Pressure and timing events were recorded with a 36-sensor HRM catheter. We analyzed the regions of the velopharynx and base of tongue for maximal pressure, rate of pressure increase, pressure gradient, and duration of pressure above baseline. In the region of the upper esophageal sphincter (UES), we analyzed duration of pressure declination, minimum pressure during opening, and maximum pressures before and after UES opening. Maneuvers did not have a significant effect on maximum pressure, rate of pressure increase, or pressure gradients in the velopharyngeal or tongue base regions. Duration of pressure above baseline was significantly longer in the velopharynx for head turn. Pre-swallow maximum UES pressure was significantly greater for neutral swallows compared to head turn and post-swallow maximum pressure was significantly lower for chin tuck. Both maneuvers appeared to prolong UES pressure declination duration, but neither reached significance. HRM allows for optimal spatial and temporal resolution during recording of pressure events along the length of the pharynx and revealed previously undetected task-dependent pressure and timing differences during chin tuck and head turn in healthy adults. These maneuvers appear to influence the UES to a greater degree than the velopharynx and tongue base. Further studies designed to quantify the effect of other maneuvers and bolus consistencies on the generation of pharyngeal pressure events in both normal and disordered subjects may lead to hypothesis-driven, optimal, individualized, swallowing therapies.
登录
查看更多内容
影响因子：
4.3
作者：
Hind, JA;Nicosia, MA;Robbins, J
通讯作者：
Robbins, J
影响因子：
29.4
作者：
KAHRILAS, PJ;LOGEMANN, JA;ERGUN, GA
通讯作者：
ERGUN, GA
影响因子：
1
作者：
Lazarus, C;Logemann, JA;Kahrilas, PJ
通讯作者：
Kahrilas, PJ
影响因子：
2.6
作者：
Bülow, M;Olsson, R;Ekberg, O
通讯作者：
Ekberg, O
影响因子：
2.6
作者：
Salassa, JR;DeVault, KR;McConnel, FMS
通讯作者：
McConnel, FMS