Measurement in vitro of pulsatile arterial diameter using a helium-neon laser.
Measurement in vitro of pulsatile arterial diameter using a helium-neon laser.
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使用氦氖激光器体外测量脉动动脉直径。
DOI：
10.1152/jappl.1987.62.2.679
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Borovetz,HS
中科院分区：
文献类型：
--
作者：
Brant,AM;Rodgers,GJ;Borovetz,HS
本文介绍了一种利用扫描光学测微仪非接触式体外测量搏动动脉直径的方法。该系统的主要部件是He-Ne激光器，其光束扫描脉动的待测动脉。激光测微仪被集成到脉动灌注仪中，对离体犬血管施加各种血流动力学条件。激光系统可靠地跟踪特定纵向位置的脉动动脉直径，以及在存在实验造成的狭窄的情况下以不同的增量跟踪。He-Ne激光测量了犬动脉和各种以端到端方式吻合的血管替代物的径向运动。根据这些新的测量，计算了动脉顺应性和弯曲应力，这两个生物力学参数被认为是吻合口内膜增生和移植物失败的潜在原因。尽管该设备本身仅限于体外使用，但它是一种潜在的有用的血管生理学和生物物理学仪器。
A noncontacting in vitro measurement of pulsatile arterial diameter using a scanning optical micrometer is described. The major component of this system is a He-Ne laser whose beam scans the pulsating artery to be measured. The laser micrometer was integrated into a pulsatile perfusion apparatus that imposed various hemodynamic conditions on excised canine vessels. The laser system reliably tracked the pulsating arterial diameter at a particular longitudinal site as well as at various increments in the presence of an experimentally created stenosis. The He-Ne laser measured the radial motion of canine arteries and various vascular substitutes anastomosed in an end-to-end fashion. From these novel measurements, calculations were made of arterial compliance and bending stress, two biomechanical parameters that are implicated as potential causes of anastomotic intimal hyperplasia and graft failure. Although this device is inherently limited to in vitro use, it is a potentially useful instrument for vascular physiology and biophysics.