Circuits controlling vertebrate locomotion: moving in a new direction.
Circuits controlling vertebrate locomotion: moving in a new direction.
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DOI:
10.1038/nrn2608
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发表时间:
2009-07
影响因子:
34.7
通讯作者:
Goulding, Martyn
中科院分区:
文献类型:
--
作者:
Goulding, Martyn
Neurobiologists have long sought to understand how circuits in the nervous system are organized and generate the precise neural outputs that underlie particular behaviors. The motor circuits in the spinal cord that control locomotion and are commonly referred to as central pattern generator (CPG) networks, provide an experimentally tractable model system for investigating how moderately complex ensembles of neurons generate select motor behaviors. The advent of novel molecular genetic techniques coupled with recent advances in our knowledge of spinal cord development means that a comprehensive understanding of how the motor circuitry is organized and operates may now be within our grasp.
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