PipMaker: a World Wide Web server for genomic sequence alignments.
PipMaker: a World Wide Web server for genomic sequence alignments.
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DOI：
10.1002/0471250953.bi1002s00
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发表时间：
2003-02-01
影响因子：
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通讯作者：
Miller, Webb
中科院分区：
文献类型：
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作者：
Elnitski, Laura;Riemer, Cathy;Miller, Webb
PipMaker是一个全球网站，用于比较两个长基因组序列并确定它们之间的保守片段。本单元介绍了PipMaker服务器的使用，并解释了生成的输出文件。PipMaker提供了一种高效的比对基因组序列的方法，并返回一种紧凑但易于解释的输出形式，即百分比同一性图(PIP)。对于两个序列之间的每个比对片段，PIP既显示相对于第一个序列的位置，又显示相似程度。PIP上的可选注释提供了其他信息，以帮助解释路线。底层blastz对齐程序的默认参数针对人-鼠标对齐进行了调整。
PipMaker is a World-Wide Web site used to compare two long genomic sequences and identify conserved segments between them. This unit describes the use of the PipMaker server and explains the resulting output files. PipMaker provides an efficient method of aligning genomic sequences and returns a compact, but easy-to-interpret form of output, the percent identity plot (pip). For each aligning segment between two sequences the pip shows both the position relative to the first sequence and the degree of similarity. Optional annotations on the pip provide additional information to assist in the interpretation of the alignment. The default parameters of the underlying blastz alignment program are tuned for human-mouse alignments.