Transmission Potential of Zika Virus by Aedes aegypti (Diptera: Culicidae) and Ae. mediovittatus (Diptera: Culicidae) Populations From Puerto Rico.
Transmission Potential of Zika Virus by Aedes aegypti (Diptera: Culicidae) and Ae. mediovittatus (Diptera: Culicidae) Populations From Puerto Rico.
复制标题
埃及伊蚊（双翅目：库蚊科）和伊蚊传播寨卡病毒的潜力。
DOI：
10.1093/jme/tjaa286
复制
发表时间：
2021
影响因子：
2.1
通讯作者：
Alto,BarryW
中科院分区：
文献类型：
--
作者：
Zimler,RebeccaA;Yee,DonaldA;Alto,BarryW
寨卡病毒在波多黎各本地传播的复发是对美国的重大公共卫生风险，美国有大量的埃及伊蚊（林奈伊蚊）和中维伊蚊（科奎莱特伊蚊）。以确定hae的程度。媒介动物是否能够传播寨卡病毒以及病毒血症对寨卡病毒的影响，我们评估了寨卡病毒在中国的感染和传播。mediovittatusandAe。利用连续稀释的传染性血液从波多黎各感染埃及蚊。高剂量的传染性血液导致两种蚊子的感染率更高。雌性埃及伊蚊对感染的易感性是雌性伊蚊的两倍。表明后一种蚊子具有更有效的中肠感染屏障。埃及伊蚊的播散性感染率高于伊蚊（40 ~ 95%）。中vitatatus(<5%)，提示在ae存在大量的中肠逃逸屏障。mediovittatus。ForAe。在摄入的寨卡病毒剂量范围内，埃及伊蚊的传播率很低，这表明唾液腺存在实质性屏障。
Recurrence of local transmission of Zika virus in Puerto Rico is a major public health risk to the United States, where mosquitoesAedes aegypti(Linnaeus) andAedes mediovittatus(Coquillett) are abundant. To determine the extent to whichAe. mediovittatusare capable of transmitting Zika virus and the influence of viremia, we evaluated infection and transmission inAe. mediovittatusandAe. aegyptifrom Puerto Rico using serial dilutions of infectious blood. Higher doses of infectious blood resulted in greater infection rates in both mosquitoes.Aedes aegyptifemales were up to twice as susceptible to infection thanAe. mediovittatus, indicating a more effective midgut infection barrier in the latter mosquito species.Aedes aegyptiexhibited higher disseminated infection (40–95%) thanAe. mediovittatus(<5%), suggesting a substantial midgut escape barrier inAe. mediovittatus. ForAe. aegypti, transmission rates were low over a range of doses of Zika virus ingested, suggesting substantial salivary gland barriers.