A plan for the next generation of HIV prevention research: Seven key policy investigative challenges
A plan for the next generation of HIV prevention research: Seven key policy investigative challenges
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DOI：
10.1037/0003-066x.59.8.747
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发表时间：
2004-11-01
影响因子：
16.4
通讯作者：
Szekeres, G
中科院分区：
文献类型：
--
作者：
Coates, TJ;Szekeres, G
虽然艾滋病毒预防研究在过去20年中取得了很大成就，但仍然存在重大挑战。这些成就包括从描述性到临床试验的各个研究阶段的快速进展，以及几个具有生物学终点的3期试验的现场。这些挑战包括在政策和结构竞技场领域制定战略和进行研究。作者概述了7个艾滋病毒政策和结构性研究挑战，以及具体的研究问题，这些问题对于研究人员在没有预防性疫苗的情况下解决未来10至20年的流行病至关重要。
Although HIV prevention research has accomplished much over the last 2 decades, significant challenges remain. The accomplishments have included rapid progression through various stages of research-from descriptive to clinical trials-and the fielding of several Phase 3 trials with biological endpoints. The challenges include developing strategies and studies in the policy and structural arena. The authors outline 7 HIV policy and structural research challenges, with specific research questions, that will be critically important as researchers move forward to address the next 10 to 20 Years of the epidemic without the benefit of prophylactic vaccines against HIV-1.