The antifungal activity of graphene oxide-silver nanocomposites
The antifungal activity of graphene oxide-silver nanocomposites
复制标题
氧化石墨烯-银纳米复合材料的抗真菌活性。
DOI：
10.1016/j.biomaterials.2013.02.001
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发表时间：
2013-05-01
期刊：
影响因子：
14
通讯作者：
Cui, Daxiang
中科院分区：
文献类型：
--
作者：
Li, Chao;Wang, Xiansong;Cui, Daxiang
氧化石墨烯基纳米复合材料的抗菌活性在临床应用中具有很大的潜力。本文首次报道了填充银纳米粒子的碳纳米卷（CNSs）的制备及其抗真菌活性的增强。利用超声法制备了填充银纳米粒子的纳米卷，TEM图像显示，纳米复合材料中填充并包裹着AgNPs。抗真菌实验表明，与直接沉积在石墨烯氧化物表面的纳米银纳米粒子制备的GO-AgNPs纳米复合材料相比，CNSs-AgNPs对白色念珠菌和热带念珠菌具有较好的抗真菌活性，这是由于CNS-AgNPs控制了银离子的持续缓释。还观察到氧化石墨烯没有抗真菌活性。综上所述，由氧化石墨烯和纳米银组成的碳纳米卷具有增强和延长的抗真菌活性，在临床医院感染和局部抗真菌治疗等方面具有很大的应用潜力。(C) 2013 Elsevier Ltd.版权所有。
Graphene oxide (GO)-based nanocomposites' antibacteria activity exhibits great potential in clinical application. Herein we reported for the first time the preparation and enhanced antifungal activity of carbon nanoscrolls (CNSs) filled with silver nanoparticles (AgNPs). The nanoscrolls filled with silver nanoparticles were prepared by sonication, TEM picture showed AgNPs filled and wrapped inside prepared nanocomposites, the antifungal test showed that CNSs-AgNPs exhibited ideal lengthened activities against Candida albicans and Candida tropical compared with the GO-AgNPs nanocomposites based on silver nanoparticles directly deposited on the surface of grapheme oxides, which is caused by CNS-AgNPs' controlled durative slow-releasing of silver ion. It is also observed that graphene oxides exhibited no antifungal activity. In conclusion, the carbon nanoscrolls composed of graphene oxides and silver nanoparticles own enhanced and lengthened antifungal activity, and have great potential in applications such as clinical nosocomial infections and local antifungal therapy. (C) 2013 Elsevier Ltd. All rights reserved.