Characteristics and outcomes of COVID-19 patients in New York City's public hospital system.

Characteristics and outcomes of COVID-19 patients in New York City's public hospital system.
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纽约市公立医院系统中Covid-19患者的特征和结果。

DOI:
10.1371/journal.pone.0243027
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发表时间:
2020
期刊:
影响因子:
3.7
通讯作者:
New York City Health + Hospitals COVID-19 Population Health Data Team
New York City Health + Hospitals COVID-19 Population Health Data Team
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Kalyanaraman Marcello R;Dolle J;Grami S;Adule R;Li Z;Tatem K;Anyaogu C;Apfelroth S;Ayinla R;Boma N;Brady T;Cosme-Thormann BF;Costarella R;Ford K;Gaither K;Jacobson J;Kanter M;Kessler S;Kristal RB;Lieber JJ;Mukherjee V;Rizzo V Jr;Rowell M;Stevens D;Sydney E;Wallach A;Chokshi DA;Davis N;New York City Health + Hospitals COVID-19 Population Health Data Team

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在大流行初期,纽约市 (NYC) 承受着美国 COVID-19 的最大负担。在本病例系列中,我们描述了在纽约市公立医院系统接受 COVID-19 检测和住院治疗的不同种族和族裔患者的特征和结果。我们审查了 2020 年 3 月 5 日至 4 月 9 日期间接受 SARS-CoV-2 检测的所有患者的电子健康记录,并随访至 2020 年 4 月 16 日。主要结果是检测呈阳性、住院和死亡。还评估了人口统计学和合并症。 22254 名患者接受了 SARS-CoV-2 检测。 13442(61%)呈阳性;其中,中位年龄为 52.7 岁(四分位距 [IQR] 39.5-64.5),其中 7481 名(56%)为男性,3518 名(26%)为黑人,4593 名(34%)为西班牙裔。近一半(4669 人,46%)患有至少一种慢性疾病(27% 患有糖尿病,30% 患有高血压,21% 患有心血管疾病)。在检测呈阳性的人中,有 6248 人(46%)住院治疗。中位年龄为 61.6 岁(IQR 49.7–72.9); 3851 名(62%)为男性,1950 名(31%)为黑人,2102 名(34%)为西班牙裔。超过一半(3269 人,53%)患有至少一种慢性病(33% 糖尿病、37% 高血压、24% 心血管疾病、11% 慢性肾病)。 1724 名住院患者(28%)死亡。中位年龄为 71.0 岁(IQR 60.0,80.9); 1087 名(63%)为男性,506 名(29%)为黑人,528 名(31%)为西班牙裔。慢性病很常见(35% 患有糖尿病,37% 患有高血压,28% 患有心血管疾病,15% 患有慢性肾病)。男性、年龄较大、糖尿病、心脏病史和慢性肾脏病与检测呈阳性、住院和死亡显着相关。所有结果均观察到种族/民族差异。这是纽约市迄今为止规模最大、种族/民族最多样化的 COVID-19 患者检测和住院病例系列。我们的研究结果强调了结果的差异,可以为预防和检测建议提供信息。
New York City (NYC) bore the greatest burden of COVID-19 in the United States early in the pandemic. In this case series, we describe characteristics and outcomes of racially and ethnically diverse patients tested for and hospitalized with COVID-19 in New York City’s public hospital system. We reviewed the electronic health records of all patients who received a SARS-CoV-2 test between March 5 and April 9, 2020, with follow up through April 16, 2020. The primary outcomes were a positive test, hospitalization, and death. Demographics and comorbidities were also assessed. 22254 patients were tested for SARS-CoV-2. 13442 (61%) were positive; among those, the median age was 52.7 years (interquartile range [IQR] 39.5–64.5), 7481 (56%) were male, 3518 (26%) were Black, and 4593 (34%) were Hispanic. Nearly half (4669, 46%) had at least one chronic disease (27% diabetes, 30% hypertension, and 21% cardiovascular disease). Of those testing positive, 6248 (46%) were hospitalized. The median age was 61.6 years (IQR 49.7–72.9); 3851 (62%) were male, 1950 (31%) were Black, and 2102 (34%) were Hispanic. More than half (3269, 53%) had at least one chronic disease (33% diabetes, 37% hypertension, 24% cardiovascular disease, 11% chronic kidney disease). 1724 (28%) hospitalized patients died. The median age was 71.0 years (IQR 60.0, 80.9); 1087 (63%) were male, 506 (29%) were Black, and 528 (31%) were Hispanic. Chronic diseases were common (35% diabetes, 37% hypertension, 28% cardiovascular disease, 15% chronic kidney disease). Male sex, older age, diabetes, cardiac history, and chronic kidney disease were significantly associated with testing positive, hospitalization, and death. Racial/ethnic disparities were observed across all outcomes. This is the largest and most racially/ethnically diverse case series of patients tested and hospitalized for COVID-19 in New York City to date. Our findings highlight disparities in outcomes that can inform prevention and testing recommendations.
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