Quartet mapping and the extent of lateral transfer in bacterial genomes
Quartet mapping and the extent of lateral transfer in bacterial genomes
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DOI：
10.1093/molbev/msg234
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发表时间：
2004-01-01
影响因子：
10.7
通讯作者：
Ochman, H
中科院分区：
文献类型：
--
作者：
Daubin, V;Ochman, H
最近的几项分析使用了基于四分法的方法来评估原核基因组中大量基因的同源性。从这些研究中得出的主要结论是，横向基因转移（LGT）已经模糊了原核生物的进化，以至于达尔文的树状进化方案可能会被抛弃，而有利于网或网。在这里，我们专注于这些方法之一，四重映射，并表明，它的应用可能会导致高估的程度推断LGT在原核生物，特别是当应用于远亲类群。
Several recent analyses have used quartet-based methods to assess the congruence among phylogenies derived for large sets of genes from prokaryotic genomes. The principal conclusion from these studies is that lateral gene transfer (LGT) has blurred prokaryotic phylogenies to such a degree that the darwinian scheme of treelike evolution might be abandoned in favor of a net or web. Here, we focus on one of these methods, quartet mapping, and show that its application can lead to overestimation of the extent of inferred LGT in prokaryotes, particularly when applied to distantly related taxa.