Separation of penicillin G from phenylacetic acid in a supported liquid membrane system
Separation of penicillin G from phenylacetic acid in a supported liquid membrane system
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DOI：
10.1002/bit.260430407
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发表时间：
1994-02
影响因子：
3.8
通讯作者：
Chan‐Jen Lee;H. Yeh;Wu‐Yung Yang;Chin‐Rang Kan
中科院分区：
文献类型：
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作者：
Chan‐Jen Lee;H. Yeh;Wu‐Yung Yang;Chin‐Rang Kan
以Amberlite LA‐2为载体，用微孔聚丙烯膜为载体，对青霉素G （Pen G）与苯乙酸（PAA）的分离进行了研究。结果表明，混合体系中各组分的渗透率均低于单室体系，表明Pen G和PAA之间存在强烈的输运竞争。本研究的SLM系统是一种很有前途的分离PAA和Pen G的方法。在液膜阻力控制机制下，最大分离系数为1.8。©1994 John Wiley & Sons, Inc
The separation of penicillin G (Pen G) from phenylacetic acid (PAA) by use of a supported liquid membrane (SLM) system with Amberlite LA‐2 dissolved in 1‐decanol, supported on a microporous polypropylene membrane, was studied. The results show that the individual permeability of each component in mixture was lower than that in a single compartment system and, it suggests a strong transport competition between Pen G and PAA. The SLM system in this study proved to be a promising process for the selective separation of Pen G from PAA. The maximum separation factor was found to be 1.8 under a liquid membrane resistance controlled mechanism. © 1994 John Wiley & Sons, Inc.