DECREASED RATE OF STUNTING AMONG ANEMIC INDONESIAN PRESCHOOL-CHILDREN THROUGH IRON SUPPLEMENTATION

DECREASED RATE OF STUNTING AMONG ANEMIC INDONESIAN PRESCHOOL-CHILDREN THROUGH IRON SUPPLEMENTATION
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DOI:
10.1093/ajcn/58.3.339
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发表时间:
1993-09-01
影响因子:
7.1
通讯作者:
SASTROAMIDJOJO, S
SASTROAMIDJOJO, S
中科院分区:
医学1区
文献类型:
--
作者:
ANGELES, IT;SCHULTINK, WJ;SASTROAMIDJOJO, S

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研究了补铁对印尼学龄前低体重贫血儿童生长和血液学状况的影响。治疗组(n = 39)每日补充30 mg Fe和20 mg维生素C,而对照组(n = 37)仅补充20 mg维生素C,为期2个月。补充分配是双盲的。在研究开始和结束时,测定体重、身高、摄食量以及血红蛋白和血清铁蛋白浓度。仅治疗组的所有血液学值均显示出显著增加(P < 0.001)。所有患儿身高、体重均增加(P < 0.01)。治疗组身高和年龄别身高Z评分的增加大于对照组(P = 0.001)。补铁对线性生长的积极影响不是由食物摄入量增加引起的,但似乎受到发病率降低的影响。铁补充剂可能是一种相对便宜的方法,以帮助减少高流行率的发育迟缓。
Effects of iron supplementation on growth and hematological status of Indonesian anemic preschool children with low weight-for-age were investigated. A treatment group (n = 39) received daily supplements of 30 mg Fe and 20 mg vitamin C, whereas a control group (n = 37) received 20 mg vitamin C only for a period of 2 mo. Supplement allocation was double blind. At the start and finish of the study, body weight, height, food intake, and hemoglobin and serum ferritin concentrations were determined. Only the treatment group showed a significant increase in all hematological values (P < 0.001). Height and weight of all children increased (P < 0.01). Increases in height and height-for-age Z score in the treatment group were larger (P = 0.001) than the increase in the control group. The positive effect of iron supplementation on linear growth was not caused by increased food intake, but seems to be influenced by decreased morbidity. Iron supplementation may be a relatively inexpensive way to help decrease the high prevalence of stunting.