Movement disorders--limb movement and the basal ganglia.

Movement disorders--limb movement and the basal ganglia.
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运动障碍——肢体运动和基底神经节。

DOI:
10.1093/ptj/71.1.60
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发表时间:
1991
期刊:
影响因子:
3.2
通讯作者:
Phillips,JG
Phillips,JG
中科院分区:
医学2区
文献类型:
--
作者:
Stelmach,GE;Phillips,JG

文献摘要

相似文献

这篇文章的主要关注点是审查实验方法,可能会导致更好地了解基底神经节在运动控制中的功能作用。考虑了基底神经节损伤的两种模型:帕金森病和亨廷顿病。综述主要集中在运动不能和运动迟缓,因为他们是基底神经节功能障碍的关键异常。一般来说,通过肌电图和运动学分析的运动,它可能是有可能的特点,具体的运动障碍。具体来说,如果中枢神经系统所遭受的损害追溯到某个结构,它可以提供有关该结构在运动控制中的参与程度和功能作用的见解。大部分的数据表明,基底神经节可能发挥特定的作用,在启动和调节力的控制。
The primary concern of this article is to review experimental methods that may lead to a better understanding of the functional role of the basal ganglia in the control of movement. Two models of basal ganglia impairment are considered: Parkinson's disease and Huntington's disease. The review focuses primarily on akinesia and bradykinesia because they are key abnormalities of basal ganglia dysfunction. In general, through electromyography and kinematic analysis of movement, it may be possible to characterize specific movement disorders. Specifically, if damage sustained by the central nervous system is traced to a certain structure, it may provide insight on the extent of involvement and functional role of that structure in the control of movement. Much of the data reviewed suggests that the basal ganglia may play a specific role in the initiation and regulation of force control.