Prevalence and correlates for interstitial cystitis symptoms in women participating in a health screening project
Prevalence and correlates for interstitial cystitis symptoms in women participating in a health screening project
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DOI：
10.1016/j.eururo.2006.08.028
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发表时间：
2007-03-01
期刊：
影响因子：
23.4
通讯作者：
Madersbacher, Stephan
中科院分区：
文献类型：
--
作者：
Temml, Christian;Wehrberger, Clemens;Madersbacher, Stephan
目标：确定间质性膀胱炎（IC）症状在城市女性人群中的患病率，研究其对生活质量和性功能的影响，并确定相关因素IC symptoms.Methods：妇女参加一个自愿健康调查项目在维也纳进行了详细的健康调查，并完成了一份问卷，其中包含的O 'Leary-Sant IC问卷。妇女与高（>= 12）的症状和问题的分数，包括失眠（> 2）和疼痛被认为是最有可能有IC.Results：共981名妇女，年龄在19至89岁（平均值，49.1 +/- 14.7岁），参加了这项研究。其中，57.9%的IC症状评分较低（评分0-3），25.9%的IC症状评分较轻（评分4-6），13.9%的IC症状评分为中度（评分7-11），2.3%的IC症状评分较高（评分12-20）。IC问题评分显示了类似的模式。IC的总体患病率为306/100，000女性，中年女性（40-59岁）的患病率最高（464/100，000）。大约三分之二的IC中度至高度风险的女性报告生活质量受损; 35%的女性报告性生活受到影响。在多变量分析中，肠道疾病（p = 0.016）和心理压力（p = 0.029）与IC的概率。结论：IC症状的患病率高于先前估计，并大大影响生活质量和性行为。(c)2006年欧洲泌尿外科协会。Elsevier B. V.出版，保留所有权利。
Objectiues: To determine the prevalence of interstitial cystitis (IC) symptoms in an urban female population, to study their impact on quality of life and sexual function, and to identify correlates for IC symptoms.Methods: Women attending a voluntary health survey project in Vienna underwent a detailed health investigation and completed a questionnaire containing the O'Leary-Sant IC questionnaire. Women with high (>= 12) symptom and problem scores including nocturia (> 2) and pain were considered most likely to have IC.Results: A total of 981 women, aged 19 to 89 yr (mean, 49.1 +/- 14.7 yr), participated in the study. Of these, 57.9% had a low IC symptom score (score 0-3), 25.9% mild IC symptoms (score 4-6), 13.9%, moderate symptoms (score 7-11), and 2.3% a high symptom score (score 12-20). The IC problem score revealed a similar pattern. The overall prevalence of IC was 306/100,000 women with the highest value (464/100,000) in middleaged women (40-59 yr). About two thirds of the women with moderate to high risk for IC reported an impairment of quality of life; 35% reported an effect on their sexual life. In a multivariate analysis, bowel disorders (p = 0.016) and psychological stress (p = 0.029) were correlated to the probability of IC.Conclusion: The prevalence of IC symptoms is higher than previously estimated and substantially affects quality of life and sexuality. (c) 2006 European Association of Urology. Published by Elsevier B.V. All rights reserved.