Corneal vascularization in the Florida manatee (Trichechus manatus latirostris) and three-dimensional reconstruction of vessels
Corneal vascularization in the Florida manatee (Trichechus manatus latirostris) and three-dimensional reconstruction of vessels
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DOI：
10.1111/j.1463-5224.2005.00351.x
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发表时间：
2005-03-01
影响因子：
1.6
通讯作者：
Reep, RL
中科院分区：
文献类型：
--
作者：
Harper, JY;Samuelson, DA;Reep, RL
佛罗里达海牛的角膜在解剖学上是独特和不寻常的，因为在整个角膜中都发现了血管。在所有其他动物物种中，这被认为是一种阻碍视力的病理状态，通常由受伤或创伤引起。本研究的目的是通过三维重建检查结构，更清楚地描述角膜血管化，以找到与性别、年龄、位置和季节相关的血管大小、分布和位置的可能模式。来自22个人的26只眼睛准备进行组织学检查和随后的三维重建。每一个被检查的样本在角膜中都有血管，平均占角膜总表面密度（体积）的0.3%。基于性别、年龄和季节的个体之间没有发现差异。环境影响也不是一个重要因素，这是最初没有预料到的。在前上皮水平存在血管是令人惊讶的，并且似乎血管化比最初认为的更向前。在一只产前眼睛中也发现了血管的存在。在所有检查的眼睛中，没有观察到损伤或创伤的迹象。基于血管的低密度、大小和位置，血管的存在似乎对视力的损害最小。血管与前上皮的关联和胎儿内血管的发育指向一种进化适应，可能是由于海牛在水体之间移动的独特能力。
The cornea of the Florida manatee is unique and unusual in its anatomy in that blood vessels have been found throughout. In all other animal species, this is considered a pathological condition impeding vision, and is usually caused by injury or trauma. The purpose of this study was to more clearly describe corneal vascularization by examining the architecture through three-dimensional reconstruction in order to find possible patterns in size, distribution, and location of blood vessels relative to gender, age, location, and season. Twenty-six eyes from 22 individuals were prepared for histologic examination and subsequent three-dimensional reconstruction. Every specimen examined had blood vessels in the cornea, comprising an average of 0.3% of total surface density (volume) of the cornea. No differences were found between individuals based on gender, age, and season. Environmental influences were not a significant factor either, which was not originally anticipated. The presence of vessels at the level of the anterior epithelium was surprising and it appeared that the vascularization was directed more anteriorly than was originally thought. The presence of blood vessels in a prenatal eye was also found. In all the eyes examined, no signs of injury or trauma could be observed. The presence of blood vessels appears to minimally impair vision based on their low density, size, and location. The association of vessels with the anterior epithelium and development of vessels within the fetus point to an evolutionary adaptation possibly due to the manatee's unique ability to move between water bodies.