HISTOLOGIC-STUDY OF THE EFFECTS OF OCCLUSAL HYPOFUNCTION FOLLOWING ANTAGONIST TOOTH EXTRACTION IN THE RAT
HISTOLOGIC-STUDY OF THE EFFECTS OF OCCLUSAL HYPOFUNCTION FOLLOWING ANTAGONIST TOOTH EXTRACTION IN THE RAT
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DOI：
10.1902/jop.1980.51.7.393
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发表时间：
1980-01-01
影响因子：
4.3
通讯作者：
MAILLAND, ML
中科院分区：
文献类型：
--
作者：
LEVY, GG;MAILLAND, ML
通过组织学研究，观察咬合功能减退对牙周组织的影响及生理性漂移过程，阐明牙周膜狭窄的原因。采用Wistar大鼠(24只)。拔除右侧上颌磨牙造成功能减退。根据经典的组织学方法，对右侧下颌骨进行固定、脱钙、切片和染色，进行组织学观察。组(2)5只动物用于补充性研究，使用顺序荧光标记来评估骨形成率。功能减退15天后，牙周膜明显变窄，结构紊乱。在神经根间隔的顶部、窝的底部和模型侧可观察到编织骨的形成。30天后，每隔3个月，牙周膜仍处于紊乱状态，变窄。新形成的骨处于成熟过程中。在神经根间隔的下部也观察到骨质疏松。荧光标记证实了组织学结果，并表明诱导骨形成与牙周韧带变窄和上萌出过程有关。
A histologic study was done to observe the influence of occlusal hypofunction on periodontal tissues and the physiologic drift process, and to elucidate the origin of periodontal ligament narrowing. Wistar rats (24) were used. Hypofunction was induced by extracting the right maxillary molars. Histologic observations were reported on the right lower jaws which were fixed, decalcified, sectioned and stained according to classical histologic methods. Groups (2) of 5 animals were used for a complementary study using sequential fluorescent labeling to evaluate the bone formation rate. After 15 days of hypofunction, the periodontal ligament was obviously narrowed and its structure was disorganized. Woven-bone formation was noted at the top of the interradicular septa, at the bottom of the sockets and along their modeling sides. At 30 days and at intervals up to 3 mo., the periodontal ligament remained disorganized and narrowed. The newly-formed bone was engaged in a maturation process. Osteoporosis was also observed at the inferior part of the interradicular septa. Fluorescent labeling confirmed the histologic findings and showed that the induced bone formation is related to periodontal ligament narrowing and the supra-eruption process.