HIPPOCAMPAL SCLEROSIS WITHOUT DETECTABLE HIPPOCAMPAL ATROPHY
HIPPOCAMPAL SCLEROSIS WITHOUT DETECTABLE HIPPOCAMPAL ATROPHY
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DOI：
10.1212/wnl.44.1.42
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发表时间：
1994-01-01
期刊：
影响因子：
9.9
通讯作者：
CASCINO, GD
中科院分区：
文献类型：
--
作者：
JACKSON, GD;KUZNIECKY, RI;CASCINO, GD
来自三个中心的 6 名患者有海马硬化的 MRI 和病理证据，但没有检测到海马萎缩。当海马体积测量正常且对称时，正常内部结构的丧失以及 T-1 和 T-2 加权信号异常使得 MRI 能够诊断单侧海马硬化。尽管在大多数情况下，准确的海马体积测量将确定受影响最严重的一侧，但仅靠体积测量或萎缩并不能总是检测出所有 MRI 可见的病理。在根据体积测量排除海马结构异常之前，需要进行额外详细的 MRI 评估。
Six patients from three centers had MRI and pathologic evidence of hippocampal sclerosis but no detectable hippocampal atrophy. Loss of normal internal structure and T-1- and T-2-weighted signal abnormalities allowed the MRI diagnosis of unilateral hippocampal sclerosis when hippocampal volume measurements were normal and symmetric. Although accurate hippocampal volume measurements will determine the most severely affected side in most cases, volume measurements or atrophy alone will not always detect all MRI-visible pathology. Additional detailed MRI assessment is required before structural abnormality of the hippocampus is excluded on the basis of volume measurements.