Good performances but short lasting efficacy of Actellic 50 EC Indoor Residual Spraying (IRS) on malaria transmission in Benin, West Africa.
Good performances but short lasting efficacy of Actellic 50 EC Indoor Residual Spraying (IRS) on malaria transmission in Benin, West Africa.
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DOI：
10.1186/1756-3305-7-256
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发表时间：
2014-05-30
影响因子：
3.2
通讯作者：
Akogbéto M
中科院分区：
文献类型：
--
作者：
Aïkpon R;Sèzonlin M;Tokponon F;Okè M;Oussou O;Oké-Agbo F;Beach R;Akogbéto M
国家疟疾防治方案在贝宁首次将甲基嘧啶磷用于室内滞留喷洒。第一轮是成功的，在接受治疗的地区，疟疾传播的昆虫学指标显著下降。我们提出的结果昆虫学对疟疾传播的影响。在对照区的昆虫学参数进行了比较，在干预网站。在阿塔科拉-东戈地区的三个区进行了苔藓采集，其中两个区（Tanguiéta和Kouandé）用甲基嘧啶磷（Actellic 50 EC）处理，未处理的区（Copargo）作为对照。冈比亚按蚊人口每月抽样人类登陆渔获量。此外，还进行了窗户出口诱捕和除虫菊喷雾诱捕，以评估媒介按蚊的外食行为。在这三个地区，组织了蚊子收集活动，以跟踪甲基嘧啶磷室内滞留喷雾杀虫剂对疟疾传播的影响以及蚊子行为的可能变化。还使用WHO生物测定测试评估了处理过的墙壁中甲基吡嘧磷的残留活性。一个显着的减少（94.25%），在人类叮咬率记录在处理区，居民收到不到1咬的安。冈比亚每晚。在同一时间内，昆虫接种率（EIR）显着下降，在处理区（99.24%的减少）。我们还注意到一个显着的减少寿命的载体和增加外亲诱导甲基嘧啶磷对安。冈比亚。然而，未发现对吸血率的显著影响。否则，Actellic 50 EC的低残留活性（三个月）是一个缺点。在贝宁，甲基嘧啶磷对室内滞留喷洒有效。然而，由于本研究中使用的Actellic 50 EC在经处理的墙壁上的持久性较低，因此需要求助于另一种残留量更大的甲基嘧啶磷制剂。
The National Malaria Control Program (NMCP) has been using pirimiphos methyl for the first time for indoor residual spraying (IRS) in Benin. The first round was a success with a significant decrease of entomological indicators of malaria transmission in the treated districts. We present the results of the entomological impact on malaria transmission. Entomologic parameters in the control area were compared with those in intervention sites. Mosquito collections were carried out in three districts in the Atacora-Dongo region of which two were treated with pirimiphos methyl (Actellic 50EC) (Tanguiéta and Kouandé) and the untreated (Copargo) served as control. Anopheles gambiae s.l. populations were sampled monthly by human landing catch. In addition, window exit traps and pyrethrum spray catches were performed to assess exophagic behavior of Anopheles vectors. In the three districts, mosquito collections were organized to follow the impact of pirimiphos methyl IRS on malaria transmission and possible changes in the behavior of mosquitoes. The residual activity of pirimiphos methyl in the treated walls was also assessed using WHO bioassay test. A significant reduction (94.25%) in human biting rate was recorded in treated districts where an inhabitant received less than 1 bite of An. gambiae per night. During this same time, the entomological inoculation rate (EIR) dramatically declined in the treated area (99.24% reduction). We also noted a significant reduction in longevity of the vectors and an increase in exophily induced by pirimiphos methyl on An. gambiae. However, no significant impact was found on the blood feeding rate. Otherwise, the low residual activity of Actellic 50 EC, which is three months, is a disadvantage. Pirimiphos methyl was found to be effective for IRS in Benin. However, because of the low persistence of Actellic 50EC used in this study on the treated walls, the recourse to another more residual formulation of pirimiphos methyl is required.