Trends in voluntary vaccination coverage in a Japanese city
Trends in voluntary vaccination coverage in a Japanese city
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DOI：
10.1111/ped.14712
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发表时间：
2021-11-08
影响因子：
1.4
通讯作者：
Kusuhara，Koichi
中科院分区：
文献类型：
--
作者：
Hoshina，Takayuki;Kawase，Mayumi;Kusuhara，Koichi
背景在日本，已经报道了大量的患者患有可通过自愿接种疫苗预防的疾病。然而，由于各国政府并不汇总未纳入国家免疫规划的疫苗接种人数，因此很难分析自愿接种疫苗对疾病预防的影响。本研究调查了两种自愿疫苗（轮状病毒疫苗和腮腺炎疫苗）的覆盖率与这些疫苗可预防疾病的发病率之间的关系。MethodsWe进行了一项前瞻性的基于问卷的观察性研究，调查了2015年至2018年北九州市婴儿期轮状病毒疫苗和1岁时腮腺炎疫苗的假定覆盖率。结果2016年以来轮状病毒疫苗和腮腺炎疫苗接种率分别为61 - 63%和28 - 30%（2015年分别为52.6%和20.3%）。2015年至2018年，每年因轮状病毒相关性胃肠炎住院的儿童人数比接种前（2009年至2011年）下降了41.4%。流行性腮腺炎感染率在调查期间保持不变。结论两种疫苗的接种率不高，不足以控制感染。将自愿接种疫苗纳入常规免疫规划是提高疫苗接种率的有效途径之一。
BackgroundLarge numbers of patients with diseases preventable by voluntary vaccines have been reported in Japan. However, it is difficult to analyze the impact of voluntary vaccination on disease prevention, as governments do not aggregate the number of recipients of vaccines that are not included in the national immunization program. This study investigated the association between the coverage rates of two voluntary vaccines (rotavirus and mumps vaccines) and the incidence of the diseases preventable by these vaccines.MethodsWe performed a prospective questionnaire‐based observational study to investigate the presumptive coverage rates of the rotavirus vaccine in infancy and the mumps vaccine at 1 year of age in Kitakyushu City from 2015 to 2018. The number of children admitted to a secondary medical institution for rotavirus‐associated gastroenteritis and the incidence of mumps infection in sentinel medical institutions were also analyzed during the investigation period.ResultsThe rotavirus and mumps vaccine coverage rates since 2016 were 61‐63% and late 28‐30%, respectively (52.6% and 20.3% in 2015, respectively). The yearly number of children hospitalized for rotavirus‐associated gastroenteritis from 2015 to 2018 declined by 41.4% compared with that during the pre‐vaccination period (2009–2011). The incidence of mumps infection remained unchanged during the investigation period.ConclusionThe coverage rates of two voluntary vaccines were not high enough to control the infections. The incorporation of voluntary vaccines into the routine immunization program should be considered as the one of the effective ways to increase vaccination coverage.