Biofilms and device-associated infections.
Biofilms and device-associated infections.
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DOI：
10.3201/eid0702.010226
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发表时间：
2001-03
影响因子：
11.8
通讯作者：
Donlan, R M
中科院分区：
文献类型：
--
作者：
Donlan, R M
微生物通常附着在生物和非生物表面，包括留置医疗器械的表面，并形成由细胞外聚合物组成的生物膜。在这种状态下，微生物对抗微生物处理具有高度抗性，并且牢固地结合到表面上。为了更好地了解和控制留置医疗器械上的生物膜，研究人员应开发可靠的采样和测量技术，研究生物膜在抗菌药物耐药性中的作用，并建立生物膜污染与患者感染之间的联系。
Microorganisms commonly attach to living and nonliving surfaces, including those of indwelling medical devices, and form biofilms made up of extracellular polymers. In this state, microorganisms are highly resistant to antimicrobial treatment and are tenaciously bound to the surface. To better understand and control biofilms on indwelling medical devices, researchers should develop reliable sampling and measurement techniques, investigate the role of biofilms in antimicrobial drug resistance, and establish the link between biofilm contamination and patient infection.