Genital warts among 18- to 59-year-olds in the United States, national health and nutrition examination survey, 1999-2004
Genital warts among 18- to 59-year-olds in the United States, national health and nutrition examination survey, 1999-2004
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DOI：
10.1097/olq.0b013e3181632d61
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发表时间：
2008-04-01
影响因子：
3.1
通讯作者：
Markowitz, Lauri E.
中科院分区：
文献类型：
--
作者：
Dinh, Thu-Ha;Sternberg, Maya;Markowitz, Lauri E.
背景：生殖器疣是由人乳头瘤病毒（HPV）引起的;超过90%是由于HPV 6和11型。我们确定了1999- 2004年美国报告被诊断患有生殖器疣的人的百分比。方法：我们收集了1999 - 2004年国家健康和营养检查调查中8849名18 - 59岁性活跃男性和女性的生殖器疣诊断史和社会人口统计学及性行为数据。总体而言，18至59奥尔兹中有5.6%报告曾被诊断患有生殖器疣。女性的百分比（7.2%，95% CI，6.2%-8.4%）高于男性（41%，95% CI，3.2%-5.0%）。生殖器疣诊断史在25- 34岁女性（10.4%）和35- 44岁男性（6.0%）中达到峰值。在多变量分析中，性别、年龄、种族/民族、终生性伴侣数量以及可卡因/街头毒品使用与生殖器疣相关。结论：这些是关于美国生殖器疣负担的首个全国数据。生殖器疣的实质性负担可以通过预防性HPV疫苗减少到6型和11型。
Background: Genital warts are caused by human papillomavirus (HPV); over 90% are due to HPV types 6 and 11. We determined the percentage of persons who reported having been diagnosed with genital warts in the United States from 1999-2004.Methods: We collected genital wart diagnosis history and sociodemographic and sexual behavior data from 8849 sexually active men and women aged 18 to 59 years as part of the National Health and Nutrition Examination Survey, 1999-2004.Results: Overall, 5.6% of 18-to 59-year olds reported having ever been diagnosed with genital warts. The percentage was higher in women (7.2%, 95% CI, 6.2%-8.4%) than in men (41%, 95% CI, 3.2%-5.0%). History of genital wart diagnosis peaked among 25- to 34-year-old women (10.4%) and 35- to 44-year-old men (6.0%). Sex, age, race/ethnicity, number of lifetime sex partners, and cocaine/street drug use were associated with genital warts in multivariate analysis.Conclusions: These are the first national data on the burden of genital warts in the United States. The substantial burden of genital warts could be reduced by a prophylactic HPV vaccine to types 6 and 11.