The ventral uvula of the mouse cerebellum: a neural target of ethanol and vestibular stimuli.
The ventral uvula of the mouse cerebellum: a neural target of ethanol and vestibular stimuli.
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小鼠小脑的腹侧悬雍垂：乙醇和前庭刺激的神经靶标。
DOI：
10.1016/j.brainres.2004.09.026
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
ScottDonovan,H
中科院分区：
文献类型：
--
作者：
Eisenman,LeonardM;ScottDonovan,H
本研究表明，暴露于垂直平移刺激的小鼠表现出独特的paraserectomy模式的Fos免疫反应（Fos-IR）颗粒细胞在腹侧悬雍垂的小脑。该模式与急性乙醇处理产生的模式相同。相比之下，偏航刺激在小脑的同一区域产生完全不同的模式。在光中或在完全黑暗中获得类似的结果。这些结果表明，腹侧悬雍垂的颗粒细胞内的解剖和功能组织，可能是一个共同的神经基板的乙醇和特定的前庭刺激的一些影响。
The present study demonstrates that mice exposed to vertical translation stimulation exhibit a distinct parasagittal pattern of Fos-immunoreactive (Fos-IR) granule cells in the ventral uvula of the cerebellum. This pattern is identical to one produced by acute ethanol treatment. In contrast, yaw stimulation produces an entirely different pattern in this same region of the cerebellum. Similar results are obtained in the light or in total darkness. These results suggest an anatomical and functional organization within the granule cells of the ventral uvula that may be a common neural substrate for some effects of ethanol and particular vestibular stimuli.