Modulation of the Relationship Between External Knee Adduction Moments and Medial Joint Contact Forces Across Subjects and Activities
Modulation of the Relationship Between External Knee Adduction Moments and Medial Joint Contact Forces Across Subjects and Activities
复制标题
跨受试者和活动的外膝内收力矩与内侧关节接触力之间关系的调节
DOI：
10.1002/art.38374
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Heller MO
中科院分区：
文献类型：
--
作者：
Trepczynski A;Kutzner I;Bergmann G;Taylor WR;Heller MO
膝关节外收力矩（EAM）通常被认为是步行过程中胫股关节载荷分布的替代指标。这项研究是进行量化的EAM和直接测量的内侧胫股接触力（Fmed）之间的关系，在一个样本的受试者在一个频谱的activity.MethodsThe EAM为9例接受全膝关节置换术的患者使用逆动力学分析计算，而遥测植入物提供Fmed为10个活动，包括步行，楼梯谈判，坐站活动，还有蹲着使用混合效应回归分析的均方根误差（RMSE）和斜率的regression.ResultsAcross科目和活动之间的关系Fmed和EAM的影响进行量化的因素“主题”和“活动”的峰值EAM和Fmed值之间的良好相关性进行了观察，与整体R2值为0.88。然而，线性回归的斜率在受试者之间的变化高达2倍。在高峰EAM和FMED，所有受试者的回归的RMSE为35%体重（%BW），而最大误差为127%BW.ConclusionThe EAM和FMED之间的关系是普遍良好的，但不同的科目和活动。这些研究结果强调的局限性，仅仅依靠EAM来推断内侧关节负荷时，过度定向cocontraction的肌肉存在，并要求进一步调查软组织相关的机制，调节在膝关节的内力。
ObjectiveThe external knee adduction moment (EAM) is often considered a surrogate measure of the distribution of loads across the tibiofemoral joint during walking. This study was undertaken to quantify the relationship between the EAM and directly measured medial tibiofemoral contact forces (Fmed) in a sample of subjects across a spectrum of activities.MethodsThe EAM for 9 patients who underwent total knee replacement was calculated using inverse dynamics analysis, while telemetric implants provided Fmedfor multiple repetitions of 10 activities, including walking, stair negotiation, sit‐to‐stand activities, and squatting. The effects of the factors “subject” and “activity” on the relationships between Fmedand EAM were quantified using mixed‐effects regression analyses in terms of the root mean square error (RMSE) and the slope of the regression.ResultsAcross subjects and activities a good correlation between peak EAM and Fmedvalues was observed, with an overall R2value of 0.88. However, the slope of the linear regressions varied between subjects by up to a factor of 2. At peak EAM and Fmed, the RMSE of the regression across all subjects was 35% body weight (%BW), while the maximum error was 127 %BW.ConclusionThe relationship between EAM and Fmedis generally good but varies considerably across subjects and activities. These findings emphasize the limitation of relying solely on the EAM to infer medial joint loading when excessive directed cocontraction of muscles exists and call for further investigations into the soft tissue–related mechanisms that modulate the internal forces at the knee.
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影响因子：
2.4
作者：
Shull, Pete B.;Shultz, Rebecca;Delp, Scott L.
通讯作者：
Delp, Scott L.
影响因子：
2.4
作者：
Goudakos, Ioannis G.;Koenig, Christian;Heller, Markus O.
通讯作者：
Heller, Markus O.
DOI：
10.1002/art.20396
发表时间：
2004-06-15
期刊：
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子：
--
作者：
Amin, S;Luepongsak, N;Felson, DT
通讯作者：
Felson, DT
影响因子：
4.7
作者：
Simic, Milena;Hunt, Michael A.;Wrigley, Tim V.
通讯作者：
Wrigley, Tim V.
影响因子：
7
作者：
Felson, D. T.
通讯作者：
Felson, D. T.