Vasoactive intestinal peptide-containing neurons in the paraventricular nucleus may participate in regulating prolactin secretion.

Vasoactive intestinal peptide-containing neurons in the paraventricular nucleus may participate in regulating prolactin secretion.
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室旁核中含有血管活性肠肽的神经元可能参与调节催乳素的分泌。

DOI:
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发表时间:
1985
影响因子:
11.1
通讯作者:
J. Kiss
J. Kiss
中科院分区:
综合性期刊1区
文献类型:
--
作者:
É. Mezey;J. Kiss

文献摘要

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血管活性肠肽(VIP)免疫反应性存在于正常对照动物下丘脑室旁核(PVN)的静脉曲张和纤维中。肾上腺切除术和哺乳结合秋水仙素治疗的结果在一个大的人口VIP免疫阳性细胞体的PVN的小细胞部分的外观。肾上腺切除术,以及哺乳,显着增加VIP阳性纤维的数量在外部区的正中隆起。这些观察结果表明,VIP免疫阳性神经元在PVN可能参与调节催乳素和促肾上腺皮质激素分泌。
Vasoactive intestinal polypeptide (VIP) immunoreactivity is present in varicosities and fibers in the hypothalamic paraventricular nucleus (PVN) in normal control animals. Adrenalectomy and lactation combined with colchicine treatment results in the appearance of a large population of VIP-immunopositive cell bodies in the parvocellular part of the PVN. Adrenalectomy, as well as lactation, significantly increases the number of VIP-positive fibers in the external zone of the median eminence. These observations suggest that the VIP-immunopositive neurons in the PVN may participate in regulating prolactin and corticotropin secretion.