Inclusion by β-cyclodextrin of a pyrene-labeled dipeptide photoprobe
Inclusion by β-cyclodextrin of a pyrene-labeled dipeptide photoprobe
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DOI：
10.1016/s0040-4039(02)01280-7
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发表时间：
2002-08-19
影响因子：
1.8
通讯作者：
Lu, LN
中科院分区：
文献类型：
--
作者：
Jones, G;Zhou, X;Lu, LN
在n端以芘片段标记的丙氨酸色氨酸二肽(1)在水中与β -环糊精紧密结合，导致光探针的荧光增强。这种效应归因于二肽的构象自由受到限制，并因此降低了发生在芘和色氨酸/吲哚基团之间的分子内电子转移速率。(C) 2002年Elsevier Science Ltd.出版
An alanyltryptophan dipeptide (1), labeled at the N-terminus with a pyrene moiety is bound strongly by beta-cyclodextrin in water, leading to enhancement of the fluorescence of the photoprobe. The effect is ascribed to restriction of conformational freedom for the dipeptide and a consequent reduction in the rate of intramolecular electron transfer that occurs between pyrene and Trp/indole moieties. (C) 2002 Published by Elsevier Science Ltd.