The differential associations of depression and diabetes distress with quality of life domains in type 2 diabetes.
The differential associations of depression and diabetes distress with quality of life domains in type 2 diabetes.
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DOI：
10.1007/s10865-013-9505-x
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发表时间：
2014-06
影响因子：
3.1
通讯作者：
Safren SA
中科院分区：
文献类型：
--
作者：
Carper MM;Traeger L;Gonzalez JS;Wexler DJ;Psaros C;Safren SA
本研究旨在了解与 2 型糖尿病 (T2DM) 成人相关的生活质量领域，以及抑郁症和糖尿病困扰与这些领域的相对关联。参与者是 146 名 T2DM 患者，他们被招募参加一项针对依从性和抑郁症的认知行为疗法的随机对照试验。我们对生活质量量表 (QOLI) 进行了探索性因素分析，以确定与该患者群体相关的生活质量领域。对每个领域的分层多元回归模型进行了评估，以确定抑郁症严重程度和糖尿病困扰与独立于人口和疾病因素的生活质量的独立关联。结果表明，四个生活质量领域：成就、心理社会成长、人际关系和环境，占 QOLI 总分方差的 60.1%。抑郁严重程度与成就、心理社会成长和环境领域的生活质量较差相关（p < 0.01），而糖尿病困扰与成就（p < 0.001）领域的生活质量较差相关，与心理社会成长（p < 0.10）领域的生活质量略有相关。与一般抑郁症干预或单独针对糖尿病的干预相比，旨在解决抑郁症和糖尿病困扰的干预措施可能会带来更好的生活质量。
The present investigation aimed to understand quality of life domains relevant to adults with type 2 diabetes mellitus (T2DM), and the relative associations of depression and diabetes distress with these domains. Participants were 146 individuals with T2DM who were recruited for entry into a randomized controlled trial of cognitive behavioral therapy for adherence and depression. We conducted an exploratory factor analysis on the Quality of Life Inventory (QOLI) to establish domains of quality of life relevant to this patient population. Hierarchical multiple regression models were evaluated for each domain that emerged to determine independent associations of depression severity and diabetes distress with quality of life independent of demographic and illness factors. Results suggested four quality of life domains: achievement, psychosocial growth, interpersonal relationships, and environment, accounting for 60.1 % of variance in total QOLI scores. Depression severity was associated with poorer quality of life on the achievement, psychosocial growth, and environment domains (p’s < 0.01), while diabetes distress was associated with poorer quality of life on the achievement (p < 0.001) domain and marginally associated with quality of life on the psychosocial growth (p < 0.10) domain. Interventions designed to address both depression and diabetes distress may lead to better quality of life outcomes than a generalized depression intervention or an intervention for diabetes alone.
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影响因子：
8.2
作者：
Gonzalez, J. S.;Delahanty, L. M.;Safren, S. A.;Meigs, J. B.;Grant, R. W.
通讯作者：
Grant, R. W.
影响因子：
3.5
作者：
Bradley, C;Todd, C;Plowright, R
通讯作者：
Plowright, R
影响因子：
16.2
作者：
Katon, WJ;Rutter, C;Von Korff, M
通讯作者：
Von Korff, M
影响因子：
16.2
作者：
Gonzalez JS;Fisher L;Polonsky WH
通讯作者：
Polonsky WH
影响因子：
8.2
作者：
Knol, MJ;Twisk, JWR;Pouwer, F
通讯作者：
Pouwer, F