Clinical evaluation of a rapid diagnostic screen (URISCREEN) for bacteriuria in children.
Clinical evaluation of a rapid diagnostic screen (URISCREEN) for bacteriuria in children.
复制标题
儿童菌尿快速诊断筛查 (URISCREEN) 的临床评估。
DOI：
10.1016/s0022-5347(01)65245-5
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
William E. Kaplan
中科院分区：
文献类型：
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作者：
Lane S. Palmer;I. Richards;William E. Kaplan
目的评估URISCREEN检测儿童显著性细菌尿的临床应用，并将其与标准定量培养进行比较。材料和方法suriscreen检测尿液样本中的过氧化氢酶，反映每毫升中至少有50,000个集落形成单位或每高倍场中至少有10个体细胞的存在。采用urisgreen和定量培养方法对200例连续接受尿动力学评估的儿童尿标本进行检测。测定敏感性、特异性、阳性预测值和阴性预测值以及准确性。结果22例假阳性，16例假阴性。敏感性65.2%，特异性85.7%，阳性预测值57.7%，阴性预测值89.2%，总体准确率81%。结论suriscreen是一种快速筛选细菌的方法。然而，高假阴性率限制了在儿科泌尿科患者的临床应用，因为检测感染是必不可少的。
PurposeWe assessed clinical use of the URISCREEN test for detecting significant bacteriuria in children and compared it to standard quantitative culture.Materials and MethodsURISCREEN detects catalase in urine samples, reflecting the presence of at least 50,000 colony-forming units per ml. or 10 somatic cells per high power field. Catheterized urine specimens from 200 consecutive children scheduled to undergo urodynamic evaluation were tested by URISCREEN and quantitative culture methods. Sensitivity, specificity, positive and negative predictive values, and accuracy were determined.ResultsOf these specimens there were 22 false-positive and 16 false-negative URISCREEN results. Sensitivity was 65.2%, specificity 85.7%, positive predictive value 57.7%, negative predictive value 89.2% and overall accuracy 81%.ConclusionsURISCREEN is a rapid screen for bacteriuria. However, the high false-negative rate limits clinical use in the pediatric urological patient for whom detecting infection is essential.