Preoperative Prediction of Verbal Episodic Memory Outcome Using fMRI
Preoperative Prediction of Verbal Episodic Memory Outcome Using fMRI
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DOI：
10.1016/j.nec.2010.12.002
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发表时间：
2011-04-01
影响因子：
2.6
通讯作者：
Binder, Jeffrey R.
中科院分区：
文献类型：
--
作者：
Binder, Jeffrey R.
这篇文章集中在一个重要的神经外科问题，其中功能成像可能有作用。颞叶癫痫手术通常包括切除大部分颞叶前部内侧，这对长期情景记忆的编码和检索至关重要。在左前颞叶切除后，30% - 60%的患者出现言语情景记忆下降。最近的研究表明，术前功能磁共振成像可以预测言语记忆变化的程度，并且与其他常规测试相结合，功能磁共振成像可以提高预测的准确性。fMRI的预测能力似乎至少与Wada记忆测试一样好，使fMRI成为术前评估Wada的可行的无创替代方案。
This article focuses on an important neurosurgical problem for which functional imaging may have a role. Temporal lobe epilepsy surgery typically involves removal of much of the anterior medial temporal lobe, which is critical for encoding and retrieval of long-term episodic memories. Verbal episodic memory decline after left anterior temporal lobe resection occurs in 30% to 60% of such patients. Recent studies show that preoperative fMRI can predict the degree of verbal memory change that will occur, and that fMRI improves prediction accuracy when combined with other routine tests. The predictive power of fMRI appears to be at least as good as the Wada memory test, making fMRI a viable noninvasive alternative to the Wada for preoperative assessment.