The Relationship between Cortical Magnification Factor and Population Receptive Field Size in Human Visual Cortex: Constancies in Cortical Architecture
The Relationship between Cortical Magnification Factor and Population Receptive Field Size in Human Visual Cortex: Constancies in Cortical Architecture
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DOI：
10.1523/jneurosci.2572-11.2011
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发表时间：
2011-09-21
影响因子：
5.3
通讯作者：
Dumoulin, Serge O.
中科院分区：
文献类型：
--
作者：
Harvey, Ben M.;Dumoulin, Serge O.
感受野（RF）大小和皮层放大因子（CMF）是视皮层的基本组织特性。随着视觉偏心率的增加，RF尺寸增加，CMF减小。RF大小和CMF之间的关系表明皮质结构的恒定性，因为它们的产品，RF（点图像）的皮质表示，可能是恒定的。以前对这个问题的动物神经生理学研究产生了相互矛盾的结果。在这里，我们使用fMRI来确定人类群体RF（pRF）和CMF之间的关系。在平均和个体数据中，CMF和pRF大小的乘积（群体点图像）接近恒定，在V1中随偏心率略微降低。CMF，pRF大小和V1表面积的半球间和受试者变化相关，人口点图像变化小于这些属性。这些结果表明，人类之间的V1皮层处理架构的大小大致恒定。向上的视觉层次，到V2，V3，hV 4，和LO 1，人口点的形象减少与偏心率，绝对值和变化率增加。PRF大小在视觉区域之间并且随着偏心率而增加，但是当以V1皮质表面区域（即，皮质皮质pRF），它们在V2/V3中的偏心率上是恒定的。因此，V2/V3，以及在某种程度上的hV 4，从V1的恒定范围采样。这可以解释人口点图像的变化在以后的地区。因此，确定pRF大小的常数因子可能不是与局部CMF的关系，而是与pRF大小和pRF采样的视觉区域中的CMF的关系。
Receptive field (RF) sizes and cortical magnification factor (CMF) are fundamental organization properties of the visual cortex. At increasing visual eccentricity, RF sizes increase and CMF decreases. A relationship between RF size and CMF suggests constancies in cortical architecture, as their product, the cortical representation of an RF (point image), may be constant. Previous animal neurophysiology studies of this question yield conflicting results. Here, we use fMRI to determine the relationship between the population RF (pRF) and CMF in humans. In average and individual data, the product of CMF and pRF size, the population point image, is near constant, decreasing slightly with eccentricity in V1. Interhemisphere and subject variations in CMF, pRF size, and V1 surface area are correlated, and the population point image varies less than these properties. These results suggest a V1 cortical processing architecture of approximately constant size between humans. Up the visual hierarchy, to V2, V3, hV4, and LO1, the population point image decreases with eccentricity, and both the absolute values and rate of change increase. PRF sizes increase between visual areas and with eccentricity, but when expressed in V1 cortical surface area (i.e., corticocortical pRFs), they are constant across eccentricity in V2/V3. Thus, V2/V3, and to some degree hV4, sample from a constant extent of V1. This may explain population point image changes in later areas. Consequently, the constant factor determining pRF size may not be the relationship to the local CMF, but rather pRF sizes and CMFs in visual areas from which the pRF samples.