Triterpenes and triterpene saponins from the stems of Akebia trifoliata
Triterpenes and triterpene saponins from the stems of Akebia trifoliata
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DOI：
10.1248/cpb.51.960
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发表时间：
2003-08-01
影响因子：
1.7
通讯作者：
Sashida, Y
中科院分区：
文献类型：
--
作者：
Mimaki, Y;Kuroda, M;Sashida, Y
为了对三叶木通的茎进行化学表征，对三叶木通茎进行了详细的植物化学检查，特别关注三萜和三萜皂苷成分，结果分离出三种新三萜 (1-3) 和三种新三萜皂苷 (11-13)，以及七种已知三萜 (4-10) 和 12 种已知三萜皂苷（14-25）。新化合物的结构是根据光谱分析确定的，包括二维核磁共振光谱数据和水解结果。四种皂苷(22-25)以良好的产率获得，并且不是从金木通茎中分离出来的，通过常规TLC检查得出结论可用作化学区分三叶木通和木通的标记化合物。据我们所知，目前的工作是对 A. trifoliata 的首次化学研究。
To characterize the stems of Akebia trifoliata chemically, a detailed phytochemical examination was carried out on A. trifoliata stems, with particular attention to the triterpene and triterpene saponin constituents, and resulted in the isolation of three new triterpenes (1-3) and three new triterpene saponins (11-13), together with seven known triterpenes (4-10) and 12 known triterpene saponins (14-25). The structures of the new compounds were determined on the basis of spectroscopic analysis, including two-dimensional NMR spectroscopic data, and the results of hydrolysis. Four saponins (22-25), which were obtained in good yields and were not isolated from Akebia quinata stems, are concluded to be applicable as marker compounds in chemically distinguishing between A. trifoliata and A. quinata by conventional TLC examination. To the best our knowledge, the current work is the first chemical investigation of A. trifoliata.