Mindfulness is associated with intrinsic functional connectivity between default mode and salience networks.
Mindfulness is associated with intrinsic functional connectivity between default mode and salience networks.
复制标题
正念与默认模式和显着性网络之间的固有功能连接有关。
DOI：
10.3389/fnhum.2015.00461
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发表时间：
2015
影响因子：
2.9
通讯作者：
Sorg C
中科院分区：
文献类型：
--
作者：
Doll A;Hölzel BK;Boucard CC;Wohlschläger AM;Sorg C
正念是不加判断地关注当下的体验。正念练习与大脑中与默认模式、突出和中央执行网络（DMN、SN、CEN）重叠的区域的活动有关。我们假设这些网络的内在功能连通性（iFC，即同步的正在进行的活动）与正念分数有关。在每天20分钟的呼吸训练2周后，健康参与者通过正念问卷和静息状态功能MRI进行评估。成像数据的独立分量分析（ICA）揭示了感兴趣的网络，其活动时间序列通过时间相关性定义了网络间的内在功能连通性（inter-iFC）。DMN和SN的子网络间的ifc以及SN和左侧CEN的子网络间的ifc与正念得分相关。关于视觉网络内部ifc的额外控制分析支持了我们研究结果的特异性。结果提供证据表明，正念与DMN和SN之间的iFC有关。数据表明，中央内在大脑网络之间的持续互动与不加判断地关注当前经验的能力有关。
Mindfulness is attention to present moment experience without judgment. Mindfulness practice is associated with brain activity in areas overlapping with the default mode, salience, and central executive networks (DMN, SN, CEN). We hypothesized that intrinsic functional connectivity (iFC; i.e., synchronized ongoing activity) across these networks is associated with mindfulness scores. After 2 weeks of daily 20 min attention to breath training, healthy participants were assessed by mindfulness questionnaires and resting-state functional MRI. Independent component analysis (ICA) of imaging data revealed networks of interest, whose activity time series defined inter-network intrinsic functional connectivity (inter-iFC) by temporal correlation. Inter-iFC between subnetworks of the DMN and SN—and inter-iFC between subnetworks of the SN and left CEN at trend—was correlated with mindfulness scores. Additional control analyses about visual networks’ inter-iFC support the specificity of our findings. Results provide evidence that mindfulness is associated with iFC between DMN and SN. Data suggest that ongoing interactions among central intrinsic brain networks link with the ability to attend to current experience without judgment.