Perspectives on HIV Prevention Among Urban Black Women: A Potential Role for HIV Pre-Exposure Prophylaxis

Perspectives on HIV Prevention Among Urban Black Women: A Potential Role for HIV Pre-Exposure Prophylaxis
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DOI:
10.1089/apc.2014.0003
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发表时间:
2014-12-01
影响因子:
4.9
通讯作者:
Mayer, Kenneth H.
Mayer, Kenneth H.
中科院分区:
医学2区
文献类型:
--
作者:
Flash, Charlene A.;Stone, Valerie E.;Mayer, Kenneth H.

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关于美国黑人妇女对局部和口服艾滋病毒暴露前预防(PrEP)的态度和可接受性的数据有限。本调查探讨了艾滋病毒化学预防和使用模式的兴趣。五个焦点小组招募了26名从市中心社区卫生中心和附属艾滋病毒检测站招募的黑人妇女。专题分析利用了“数据库”。大多数女性表示对PrEP感兴趣,因为许多女性报告了避孕套失效的担忧。大多数女性更喜欢药丸配方阴道内凝胶,因为更大的隐私和对阴道副作用和凝胶泄漏的担忧。以前服用过避孕药的妇女主张每天服用一次,并表示对偶发性或性交后PrEP的依从性担忧。许多妇女希望采取包括伴侣检测在内的预防策略。城市黑人女性对使用PrEP感兴趣;然而,对凝胶的不便和对自己及其伴侣的潜在副作用存在疑虑。大多数女性更喜欢口服PrEP,每天服用。
Limited data exist regarding attitudes and acceptability of topical and oral HIV pre-exposure prophylaxis (PrEP) among US black women. This investigation explored interest in HIV chemoprophylaxis and modes of use. Five focus groups enrolled 26 black women recruited from an inner-city community health center and affiliated HIV testing sites. Thematic analysis utilized Atlas.ti. Most women expressed interest in PrEP, as many reported condom failure concerns. Most women preferred a pill formulation to intravaginal gel because of greater perceived privacy and concerns about vaginal side effects and gel leakage. Women who had taken pills previously advocated daily dosing and indicated adherence concerns about episodic or post-coital PrEP. Many women desired prophylactic strategies that included partner testing. Urban black women are interested in utilizing PrEP; however, misgivings exist about gel inconvenience and potential side effects for themselves and their partners. Most women preferred oral PrEP, dosed daily.