Hot brownian particles and photothermal correlation spectroscopy.
Hot brownian particles and photothermal correlation spectroscopy.
复制标题
热布朗粒子和光热相关光谱。
DOI：
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发表时间：
2009
影响因子：
2.9
通讯作者：
F. Cichos
中科院分区：
文献类型：
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作者：
Romy Radünz;D. Rings;K. Kroy;F. Cichos
我们介绍了一种测量示踪剂动力学的新技术，该技术对半径为2.5 nm的单个金属纳米粒子具有几微秒的时间分辨率。它是基于对激光加热示踪器周围的热晕发出的外差式光热散射信号的涨落分析。建立并验证了“热布朗运动”的广义斯托克斯-爱因斯坦关系。利用金纳米颗粒优异的光稳定性，该方法具有广阔的应用前景，特别是在定量生物医学筛选领域。
We introduce a new technique to measure tracer dynamics, which is sensitive to single metal nanoparticles down to a radius of 2.5 nm with a time resolution of a few microseconds. It is based on a fluctuation analysis of a heterodyne photothermal scattering signal emanating from the hot halo around the laser-heated tracer. A generalized Stokes-Einstein relation for "hot brownian motion" is developed and verified. Exploiting the excellent photostability of gold nanoparticles, the developed method promises broad applications especially in the field of quantitative biomedical screening.