Comparative histological studies of the tunable dye (at 577 nm) laser and argon laser: the specific vascular effects of the dye laser.
Comparative histological studies of the tunable dye (at 577 nm) laser and argon laser: the specific vascular effects of the dye laser.
复制标题
可调谐染料（577 nm）激光和氩激光的比较组织学研究：染料激光的特定血管效应。
DOI：
10.1111/1523-1747.ep12482476
复制
发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Parrish,JA
中科院分区：
文献类型：
--
作者：
Greenwald,J;Rosen,S;Anderson,RR;Harrist,T;MacFarland,F;Noe,J;Parrish,JA
这项研究比较了氩激光和染料激光(波长为577 nm)治疗正常人皮肤后发生的组织学变化。氩激光的最初作用是弥漫性非特异性表皮和上层真皮坏死，随后细胞死亡，48小时出现中性粒细胞反应。这些变化发生在15焦耳/厘米~2处，其程度与所施加的能量密切相关。与之形成鲜明对比的是，染料激光的直接作用是红细胞聚集、血管破裂和出血。48小时时，真皮上部出现急性血管炎，真皮中部出现明显的血管周围中性粒细胞反应。局部表皮坏死确实发生，但相对较小，而皮肤附件和胶原蛋白被保存下来。产生这些变化的能量相对较小，约为3J/cm2。因此，577 nm染料激光可以选择性损伤皮肤血管丛，可能为皮肤血管病变的治疗提供依据。
This study compares the histological changes occurring after argon laser and dye laser (operating at 577 nm) treatment of normal human skin. The initial effect of the argon laser is a diffuse nonspecific epidermal and upper dermal necrosis with subsequent cell death and a neutrophilic response at 48 hr. These changes occur at 15 joules/cm2and their extent closely correlates with the energy applied. In sharp contrast, the immediate effect of the dye laser is erythrocyte aggregation, vessel rupture, and hemorrhage. At 48 hr, there is a pattern of acute vasculitis in the upper dermis and a prominent perivascular neutrophilic response in the mid-dermis. Focal epidermal necrosis does occur but is relatively minimal, while skin appendages and collagen are preserved. The energy to produce these alterations is relatively small, approximately 3 J/cm2. Thus, the dye laser at 577 nm can selectively damage the cutaneous vascular plexus and may provide a basis for treatment of cutaneous vascular lesions.
影响因子：
56.9
作者：
Edkins, S. D.;Kostin, A.;Hamidian, M. H.
通讯作者：
Hamidian, M. H.