Molecular characterization of Cryptosporidium from various hosts

Molecular characterization of Cryptosporidium from various hosts
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DOI:
10.1017/s0031182098002765
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发表时间:
1998-07-01
期刊:
影响因子:
2.4
通讯作者:
Thompson, RCA
Thompson, RCA
中科院分区:
医学2区
文献类型:
--
作者:
Morgan, UM;Sargent, KD;Thompson, RCA

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A 298 bp region of the Cryptosporidium parvum 18S rDNA and a 390 bp region of the acetyl-CoA synthetase gene were sequenced for a range of human and animal isolates of Cryptosporidium from different geographical areas. A distinct genotype is common to isolates from cattle, sheep and goats and also an alpaca from Peru and is referred to here as the 'calf'-derived Cryptosporidium genotype. Another genotype of 'human'-derived isolates also appears to be conserved amongst human isolates although humans are also susceptible to infection-with the 'calf' Cryptosporidium genotype. Mice and pigs carry genetically distinct genotypes of Cryptosporidium. Three snake isolates were also analysed, 2 of which exhibited C. muris genotypes and the third snake isolate carried a distinct 'mouse' genotype.