Genetic contribution to variation in larval development time, adult size, and longevity of starved adults of Anopheles gambiae
Genetic contribution to variation in larval development time, adult size, and longevity of starved adults of Anopheles gambiae
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DOI：
10.1016/j.meegid.2006.01.007
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发表时间：
2006-09-01
影响因子：
3.2
通讯作者：
Dujardin, Jean Pierre
中科院分区：
文献类型：
--
作者：
Lehmann, Tovi;Dalton, Ryan;Dujardin, Jean Pierre
人们已经根据环境因素研究了蚊子生活史特征（例如成虫体型）的变化，但几乎没有考虑遗传对这种变化的贡献。利用野生捕获的冈比亚按蚊（M 分子形式）雌性产生的 F1 的全同胞设计，我们估计了幼虫发育时间、成虫体型（基于干重和翅膀长度）和饥饿成虫的寿命的广义遗传力。这些性状在雌性和配偶中彼此相关（在表型水平）（竖线 r(p)竖线 > 0.5，P < 0.001）。饥饿成虫的寿命随着成虫体型的增大而增加，而这两个性状（成虫寿命和体型）随着幼虫发育的延长而下降。遗传相关性较低（垂直条 r(g) 垂直条 > 0.45，P < 0.05），但提供了一致的证据，反对成虫大小和幼虫发育时间之间的权衡，预测蚊子可以更快地发育成较小的成虫，或者通过较长的发育成为较大的成虫。这三个性状的遗传力估计为中等到高（范围：0.05-0.48）并且具有统计显着性（P < 0.05），表明遗传对这些性状的表型变异有很大的贡献。这些结果表明，冈比亚疟原虫种群之间的这些性状可能存在适应性差异。 (c) 2006 Elsevier B.V. 保留所有权利。
The variation in mosquito life-history traits such as adult size has been studied with respect to environmental factors, but the genetic contribution to such variation has received almost no consideration. Using a full-sib design of F1s produced by wild caught Anopheles gambiae (M molecular form) females, we estimated broad-sense heritability of larval developmental time, adult size (based on dry weight and wing length), and longevity of starved adults. These traits were correlated (at the phenotypic level) with each other in females and mates (vertical bar r(p)vertical bar > 0.5, P < 0.001). Longevity of starved adults increased with adult size, and both traits (adult longevity and size) decreased with longer larval development. Genetic correlations were lower (vertical bar r(g)vertical bar > 0.45, P < 0.05) but provided consistent evidence against a trade off between adult size and larval development time predicting that a mosquito can develop faster into a smaller adult or be a larger adult by a longer development. Estimates of heritability of the three traits were moderate to high (range: 0.05-0.48) and statistically significant (P < 0.05), indicating substantial genetic contribution to the phenotypic variation in these traits. These results suggest that adaptive differences are likely to be found in these traits between A. gambiae populations. (c) 2006 Elsevier B.V. All rights reserved.