[A case of high FDG-uptake into the myocardium after radiotherapy for esophageal cancer].
[A case of high FDG-uptake into the myocardium after radiotherapy for esophageal cancer].
复制标题
食管癌放疗后心肌高FDG摄取一例[J].
DOI：
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发表时间：
2005
期刊：
影响因子：
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通讯作者：
S. Yamada
中科院分区：
文献类型：
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作者：
K. Jingu;K. Nemoto;T. Kaneta;Y. Takai;A. Ichinose;Y. Ogawa;S. Yamada
在接受过纵隔辐射的患者中观察到了辐射引起的心脏病。一位68岁的男性，曾接受过食道癌的放化疗，放射治疗6个月后，他的心肌显示出高FDG摄取。高摄取FDG的区域与照射野相匹配。该区域在Gd-MRI上也表现为低摄取~(123)I-BMIPP和延迟强化。这些发现提示了放射性心肌病的可能性。目前已有多项研究通过灌注成像检测放射性心肌病，但利用代谢成像或MRI检测放射性心肌病的研究较少。FDG-PET和123I-BMIPP Gd-MRI可早期显示和量化放射性心肌病的程度。
Radiation-induced cardiac disease has been observed in patients who have been irradiated to the mediastinum. A 68-year-old man who had been treated with chemoradiotherapy for esophageal cancer showed high FDG-uptake in his myocardium six months after the radiotherapy. The area of high FDG-uptake closely matched the irradiation field. This area also showed low 123I-BMIPP-uptake and delayed enhancement on Gd-MRI. These findings suggested the likelihood of radiation cardiomyopathy. There have been several studies on the detection of radiation cardiomyopathy by perfusion imaging, but few on detection by metabolic imaging or MRI. Early visualization and quantification of the degree of radiation cardiomyopathy might be possible by FDG-PET and 123I-BMIPP Gd-MRI.