Amino acid sequence homology among the major outer membrane proteins of Escherichia coli.
Amino acid sequence homology among the major outer membrane proteins of Escherichia coli.
复制标题
大肠杆菌主要外膜蛋白的氨基酸序列同源性。
DOI：
10.1073/pnas.81.4.1048
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发表时间：
1984
影响因子：
11.1
通讯作者：
Wu,HC
中科院分区：
文献类型：
--
作者：
Nikaido,H;Wu,HC
大肠杆菌的主要外膜蛋白，包括孔蛋白（OmpF，OmpC，和PhoE），噬菌体λ受体（LamB），和另一种蛋白质（OmpA）的氨基酸序列的分析报告，揭示了几个地区的局部同源性是统计学上显着的。这一观察结果的影响进行了讨论，这些蛋白质的进化起源，以及这些蛋白质的出口到外膜的机制。
Analysis of amino acid sequences reported for the major outer membrane proteins of Escherichia coli, including the porins (OmpF, OmpC, and PhoE), the phage lambda receptor (LamB), and another protein (OmpA), revealed several regions of local homology that is statistically significant. The implications of this observation are discussed in relation to the evolutionary origins of these proteins, as well as to the mechanism of export of these proteins to the outer membrane.