Photodynamic antimicrobial activity of avian eggshell pigments
Photodynamic antimicrobial activity of avian eggshell pigments
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DOI：
10.1016/j.febslet.2009.12.041
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发表时间：
2010-02-19
期刊：
影响因子：
3.5
通讯作者：
Itoh, Makoto
中科院分区：
文献类型：
--
作者：
Ishikawa, Shin-ichi;Suzuki, Kazuto;Itoh, Makoto
Pigmentation in avian eggshells appears to be associated with shell strength, temperature regulation, and camouflage. The pigments found in eggshells are mainly porphyrins, which have been utilized therapeutically as photosensitizers. Here, we examined the photoinactivation of gram-positive (Staphylococcus aureus, Bacillus cereus) and gram-negative bacteria (Escherichia coli, Salmonella enteritidis) by hen eggshells and their pigments. The results indicated that eggshells have a light-dependent antimicrobial activity against gram-positive, but not gram-negative, bacteria. Our results indicate the possibility that the natural pigments used therapeutically have evolved in nature as a defence system. (C) 2009 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.
