Is Kawasaki disease incidence rising in Chandigarh, North India?
Is Kawasaki disease incidence rising in Chandigarh, North India?
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DOI：
10.1136/adc.2010.194001
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发表时间：
2011-02-01
影响因子：
5.2
通讯作者：
Burns, Jane C.
中科院分区：
文献类型：
--
作者：
Singh, Surjit;Aulakh, Roosy;Burns, Jane C.
目的估计川崎（KD）的发病率随时间的推移在城市的昌迪加尔，北India.Patients和方法，我们分析了15岁以下的儿童在儿科过敏免疫学单位，高级儿科中心，研究生院医学教育和研究，昌迪加尔，从1994年1月至2008年12月的所有儿童KD的记录。川崎病的诊断和治疗以美国心脏协会标准为依据。在这些病例中，查明了居住在昌迪加尔的儿童。结果1994 ~ 2008年共确诊川崎病患儿196例。其中80人（40.8%; 48名男孩，32名女孩）居住在昌迪加尔。其中4例在超声心动图上有冠状动脉异常（CAA），2例有二尖瓣返流。对年度数据的比较显示，发病率从1994年的每10万名15岁以下儿童0.51例增加到2007年的4.54例。大多数病例（93.7%）发生在儿童中
Objective To estimate incidence of Kawasaki disease (KD) over time among children in the city of Chandigarh, North India.Patients and methods We analysed records of all children with KD below 15 years of age at the Pediatric Allergy Immunology Unit, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, from January 1994 to December 2008. Diagnosis and treatment of KD were based on American Heart Association criteria. Among these cases, children residing in Chandigarh were identified. Yearly incidence was calculated and compared from 1994 to 2008.Results During this period, 196 children were diagnosed as KD. Of these, 80 (40.8%; 48 boys, 32 girls) resided in Chandigarh. Four among these had coronary artery abnormalities (CAA) on echocardiography, while two had mitral regurgitation. Comparison of yearly data revealed increasing incidence of disease from 0.51 cases in 1994 to 4.54 cases per 100 000 children below 15 years of age in 2007. Majority (93.7%) of cases occurred in children